Precision Probing of O-GalNAc Glycosylation Using Bump-and-Hole Engineering

Glycosylation is a profound influencer of glycoprotein function. Glycans have a critical impact on health and disease, yet the tools to study them have trailed behind proteins and nucleic acids. O-GalNAc glycosylation involves the addition of N-acetylgalactosamine (GalNAc) to protein substrates. Dys...

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Bibliographic Details
Main Authors: Abdul Zafar, Benjamin Schumann
Format: Article
Language:deu
Published: Swiss Chemical Society 2025-03-01
Series:CHIMIA
Subjects:
Online Access:https://www.chimia.ch/chimia/article/view/7891
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