Combined metformin and simvastatin therapy inhibits SREBP2 maturation and alters energy metabolism in glioma

Combined metformin and simvastatin therapy inhibits SREBP2 maturation and alters energy metabolism in glioma

Abstract This study aims to explore the inhibitory effects of combined metformin and simvastatin therapy on the malignant progression of glioma. The research specifically examines how the maturation of SREBP2 as a transcription factor affects the expression of GLUT1 and GLUT6 in glioma cells. Additi...

Full description

Saved in:
Bibliographic Details
Main Authors: Xiaolong Qiao, Zixuan Wang, Yinan Chen, Nan Peng, Hongwei Zhang, Chaoshi Niu, Chuandong Cheng
Format: Article
Language:English
Published: Nature Publishing Group 2024-11-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-024-07169-5
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items