Progress of personalized medicine of cystic fibrosis in the times of efficient CFTR modulators
Abstract Background Cystic fibrosis (CF) is a systemic disorder of exocrine glands that is caused by mutations in the CFTR gene. Main body The basic defect in people with CF (pwCF) leads to impaired epithelial transport of chloride and bicarbonate that can be assessed by CFTR biomarkers, i.e. the β-...
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| Main Authors: | Burkhard Tümmler, Sophia Theres Pallenberg, Anna-Maria Dittrich, Simon Y. Graeber, Lutz Naehrlich, Olaf Sommerburg, Marcus A. Mall |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SpringerOpen
2025-05-01
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| Series: | Molecular and Cellular Pediatrics |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s40348-025-00194-0 |
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