Factors influencing hepatitis B vaccination intention and behavior among college students in Tibet: Insights from the expanded theory of planned behavior

Hepatitis B (Hep B) remains a critical public health issue globally, particularly in Tibet, where vaccination rates and influencing factors among college students are yet understudied. This study applies a cross-sectional design to investigate the Hep B vaccination rate among 1,126 college students...

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Main Authors: Qi Chen, Jun Ma, Ruipeng Wu, Yingting Wang, Xiaoxin Ma, Xiaolei Zheng, Hui Jin
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Human Vaccines & Immunotherapeutics
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Online Access:https://www.tandfonline.com/doi/10.1080/21645515.2025.2452026
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author Qi Chen
Jun Ma
Ruipeng Wu
Yingting Wang
Xiaoxin Ma
Xiaolei Zheng
Hui Jin
author_facet Qi Chen
Jun Ma
Ruipeng Wu
Yingting Wang
Xiaoxin Ma
Xiaolei Zheng
Hui Jin
author_sort Qi Chen
collection DOAJ
description Hepatitis B (Hep B) remains a critical public health issue globally, particularly in Tibet, where vaccination rates and influencing factors among college students are yet understudied. This study applies a cross-sectional design to investigate the Hep B vaccination rate among 1,126 college students in Tibet and utilizes the expanded theory of planned behavior (ETPB) to identify vaccination behavior intention (BI) and vaccination behavior (VB). Stratified cluster sampling across three universities was used to assess behavioral attitudes (BA), subjective norms (SN), perceived behavioral control (PBC), past vaccination history (PVH) and vaccination knowledge (VK), and used structural equation modeling (SEM) for model validation and multi-group comparison. Results indicated that 16.3% of students had received the Hep B vaccine. VK notably improved BA toward vaccination (β = 0.518, p < .001). BA (β = 0.232, p < .001), PBC (β = 0.239, p < .001), SN (β = 0.385, p < .001) positively influenced BI. However, PVH failed to predict BI. BI (β = 0.448, p < .001) and PVH (β = 0.127, p < .001) were significant predictors of VB. Significant ethnic variations were noted. The positive effect of PVH on VB (β = 0.151, p < .001) and the mediating role of PBC in VB (β = 0.076, p < .05) were significant among Tibetan students. The effect of VK on BA was stronger among Tibetans (β = 0.503, p < .05),while the impact of attitude on BI was more pronounced among Han students (β = 0.366, p < .05). The vaccination rate for Hep B among college students in Tibet is relatively low, and the ETPB model effectively explains their vaccination intentions and behaviors. Tailored intervention strategies for Tibetan and Han students are recommended to boost vaccination rates effectively.
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spelling doaj-art-cdd1a5a215e24617b4b5c1a194c783c02025-01-16T13:59:09ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2025-12-0121110.1080/21645515.2025.2452026Factors influencing hepatitis B vaccination intention and behavior among college students in Tibet: Insights from the expanded theory of planned behaviorQi Chen0Jun Ma1Ruipeng Wu2Yingting Wang3Xiaoxin Ma4Xiaolei Zheng5Hui Jin6Department of Epidemiology and Health Statistics, School of Public Health, Southeast University, Nanjing, PR ChinaDepartment of Epidemiology and Health Statistics, School of Public Health, Southeast University, Nanjing, PR ChinaKey Laboratory for Molecular Genetic Mechanisms and Intervention Research on High Altitude Disease of Tibet Autonomous Region, School of Medicine, Xizang Minzu University, Xianyang, P.R. ChinaKey Laboratory for Molecular Genetic Mechanisms and Intervention Research on High Altitude Disease of Tibet Autonomous Region, School of Medicine, Xizang Minzu University, Xianyang, P.R. ChinaDepartment of General Practice, Chengguan Liangdao Subdistrict Community Health Service Center, Lhasa, PR ChinaDepartment of General Practice, Chengguan Liangdao Subdistrict Community Health Service Center, Lhasa, PR ChinaDepartment of Epidemiology and Health Statistics, School of Public Health, Southeast University, Nanjing, PR ChinaHepatitis B (Hep B) remains a critical public health issue globally, particularly in Tibet, where vaccination rates and influencing factors among college students are yet understudied. This study applies a cross-sectional design to investigate the Hep B vaccination rate among 1,126 college students in Tibet and utilizes the expanded theory of planned behavior (ETPB) to identify vaccination behavior intention (BI) and vaccination behavior (VB). Stratified cluster sampling across three universities was used to assess behavioral attitudes (BA), subjective norms (SN), perceived behavioral control (PBC), past vaccination history (PVH) and vaccination knowledge (VK), and used structural equation modeling (SEM) for model validation and multi-group comparison. Results indicated that 16.3% of students had received the Hep B vaccine. VK notably improved BA toward vaccination (β = 0.518, p < .001). BA (β = 0.232, p < .001), PBC (β = 0.239, p < .001), SN (β = 0.385, p < .001) positively influenced BI. However, PVH failed to predict BI. BI (β = 0.448, p < .001) and PVH (β = 0.127, p < .001) were significant predictors of VB. Significant ethnic variations were noted. The positive effect of PVH on VB (β = 0.151, p < .001) and the mediating role of PBC in VB (β = 0.076, p < .05) were significant among Tibetan students. The effect of VK on BA was stronger among Tibetans (β = 0.503, p < .05),while the impact of attitude on BI was more pronounced among Han students (β = 0.366, p < .05). The vaccination rate for Hep B among college students in Tibet is relatively low, and the ETPB model effectively explains their vaccination intentions and behaviors. Tailored intervention strategies for Tibetan and Han students are recommended to boost vaccination rates effectively.https://www.tandfonline.com/doi/10.1080/21645515.2025.2452026Expanded theory of planned behavior (ETPB)Tibetan college studentshepatitis B vaccinationstructural equation modeling (SEM)vaccination behavior determinants
spellingShingle Qi Chen
Jun Ma
Ruipeng Wu
Yingting Wang
Xiaoxin Ma
Xiaolei Zheng
Hui Jin
Factors influencing hepatitis B vaccination intention and behavior among college students in Tibet: Insights from the expanded theory of planned behavior
Human Vaccines & Immunotherapeutics
Expanded theory of planned behavior (ETPB)
Tibetan college students
hepatitis B vaccination
structural equation modeling (SEM)
vaccination behavior determinants
title Factors influencing hepatitis B vaccination intention and behavior among college students in Tibet: Insights from the expanded theory of planned behavior
title_full Factors influencing hepatitis B vaccination intention and behavior among college students in Tibet: Insights from the expanded theory of planned behavior
title_fullStr Factors influencing hepatitis B vaccination intention and behavior among college students in Tibet: Insights from the expanded theory of planned behavior
title_full_unstemmed Factors influencing hepatitis B vaccination intention and behavior among college students in Tibet: Insights from the expanded theory of planned behavior
title_short Factors influencing hepatitis B vaccination intention and behavior among college students in Tibet: Insights from the expanded theory of planned behavior
title_sort factors influencing hepatitis b vaccination intention and behavior among college students in tibet insights from the expanded theory of planned behavior
topic Expanded theory of planned behavior (ETPB)
Tibetan college students
hepatitis B vaccination
structural equation modeling (SEM)
vaccination behavior determinants
url https://www.tandfonline.com/doi/10.1080/21645515.2025.2452026
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