Model-Based Dose Identification of Dalbavancin for Long-Term Suppressive Outpatient Treatment of Ventricular Assist Device Infections

Model-Based Dose Identification of Dalbavancin for Long-Term Suppressive Outpatient Treatment of Ventricular Assist Device Infections

Increasing evidence suggests that dalbavancin is an effective long-term treatment for ventricular assist device (VAD) infections, with various prolonged dosing regimens currently in use. This retrospective study aimed to assess dalbavancin pharmacokinetics in VAD patients and identify optimal, feasi...

Full description

Saved in:

Bibliographic Details
Main Authors:	Ute Chiriac, Uwe Liebchen, Otto Roman Frey, Heike Lanzinger, Sabrina Klein, Torsten Hoppe-Tichy, Matthias Karck, Anna Meyer, Benedict Morath
Format:	Article
Language:	English
Published:	MDPI AG 2024-11-01
Series:	Antibiotics
Subjects:	dalbavancin ventricular assist device population pharmacokinetics therapeutic drug monitoring long-term treatment
Online Access:	https://www.mdpi.com/2079-6382/13/11/1103
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Strategies to Stabilize Dalbavancin in Aqueous Solutions; Section-2: The Effects of 2 Hydroxypropyl-β-Cyclodextrin and Acetate Buffer with and Without Divalent Metal Ions
by: Sardar M. Jakaria, et al.
Published: (2024-11-01)

Off-Label Use of Dalbavancin in <i>Enterococcus</i> spp. Abscess and <i>Streptococcus pneumoniae</i> Bacteremia Secondary to Septic Arthritis: A Retrospective Case Report
by: Miriam Banoub Morkos, et al.
Published: (2024-09-01)

Using Dalbavancin for the Treatment of Acute Bacterial Skin and Skin Structure Infections (ABSSSIs) in Obese Patients: A Real-Life, Single-Center Observational Study
by: Alessandra Oliva, et al.
Published: (2025-01-01)

Dalbavancin Use in Bone and Joint Infections
by: Liam P. Alderson, BS, et al.
Published: (2024-12-01)

Safety and Efficacy of Dalbavancin in Real Life: Retrospective Analysis of a Large Monocentric Case Series of Patients Treated for Skin/Soft Tissue and Other Difficult-to-Treat Infections
by: Giustino Parruti, et al.
Published: (2024-11-01)

Effect of preoperative right ventricular dysfunction and dilatation on survival after left ventricular surgical restoration
by: Abdelhameed Elsayed, et al.
Published: (2025-01-01)

Case Report: Left ventricular assist device implantation combined with cryoballoon ablation for ventricular tachycardia
by: Shuang Zhang, et al.
Published: (2025-01-01)

Slow ventricular tachycardia induced by amiodarone overdose
by: Zachary Boivin, et al.
Published: (2023-12-01)

Methodological Study of Reliability Test of Percutaneous Ventricular Assist Device
by: Xun LIU, et al.
Published: (2024-01-01)

Echocardiographic Grading of Right Ventricular Afterload in Left Heart Disease: Relation to Right Ventricular Function, Pulsatile and Resistant Load, and Outcome
by: Odd Bech‐Hanssen, et al.
Published: (2024-10-01)

Comparative Efficacy of Amiodarone and Lidocaine in Treating Cardiac Arrest Due to Ventricular Fibrillation and Pulseless Ventricular Tachycardia in Adults. A Literature Review
by: Patryk Dryja, et al.
Published: (2024-12-01)

Noninvasive Evaluation of Left Ventricular-Arterial Coupling: Methodologies and Clinical Relevance
by: Xin Zhang, MD, Yun Yang, MD, Ruize Zhang, MD, Linyue Zhang, MD, Yuji Xie, MD, Wenqian Wu, MD, PhD, Jing Zhang, MD, PhD, Qing Lv, MD, PhD, Jing Wang, MD, PhD, Mingxing Xie, MD, PhD
Published: (2024-12-01)

Rapid left ventricular dimension normalization following transcatheter ventricular septal defect closure in children
by: Hui Yuan, et al.
Published: (2025-02-01)

Natural Course of Electrocardiographic Features in Arrhythmogenic Right Ventricular Cardiomyopathy and Their Relation to Ventricular Arrhythmic Events
by: Anneli Svensson, et al.
Published: (2024-08-01)

Left ventricular perforation by Impella 5.5 during surgery for postinfarction ventricular septal rupture
by: Hisato Ito, et al.
Published: (2024-11-01)

Assessment of ECG Criteria for the Diagnosis of Right Ventricular Involvement
by: Suhaib Al-Mashari, et al.
Published: (2024-07-01)

Evaluation of left ventricular systolic function in patients with iron deficiency anemia based on non-invasive left ventricular pressure–strain loops
by: Xiuxiu Cui, et al.
Published: (2024-08-01)

THE RISK OF PREMATURE VENTRICULAR CONTRACTIONS DEPENDING ON PARAMETERS OF THE LEFT VENTRICULAR SYSTOLIC FUNCTION AMONG PATIENTS WITH ACUTE MYOCARDIAL INFARCTION
by: E. V. Sid, et al.
Published: (2019-04-01)

Iron in ventricular remodeling and aneurysms post-myocardial infarction
by: Wang Zuoyan, et al.
Published: (2024-12-01)

Sustained Ventricular Tachycardia as the first presentation of transthyretin amyloid cardiomyopathy
by: Hugo R. Ramos, et al.
Published: (2024-12-01)

Concurrent left ventricular pseudoaneurysm and ventricular septal rupture complicating an inferior myocardial infarction: A case report
by: Yosra Abdulahad Turkistani, MD, et al.
Published: (2025-02-01)

Myocardial Ventricular Noncompaction: Recent Literature Due to its Rarity in Childhood
by: Osman Güvenç, et al.
Published: (2015-08-01)

A rare phenomenon involving ventricular separation: a case report
by: Huayong Jin, et al.
Published: (2024-12-01)

Treatment of arrhythmogenic right ventricular cardiomyopathy (dysplasia)
by: M.Т. Vatutin, et al.
Published: (2016-03-01)

Left ventricular remodeling and its association with mineral and bone disorder in kidney transplant recipients
by: Li Sun, et al.
Published: (2024-12-01)

Predictive value of epicardial fat thickness for left ventricular reverse remodeling after radiofrequency ablation in atrial fibrillation patients with left ventricular hypertrophy
by: Ke Hu, et al.
Published: (2025-01-01)

Right ventricular failure due to subacute massive pulmonary embolism
by: Claudio Giumelli, et al.
Published: (2025-02-01)

Surgical treatment of left ventricular aneurysm of posterior basal localization
by: V.I. Ursulenko, et al.
Published: (2017-06-01)

Experience with left ventricular assist device usage in the treatment of end-stage heart failure
by: B.M. Todurov, et al.
Published: (2017-06-01)

Sustained polymorphic ventricular tachycardia in a calf
by: Amir Naseri, et al.

Differentiating Apical and Basal Left Ventricular Aneurysms Using Sphericity Index: A Clinical Study
by: Slobodan Tomić, et al.
Published: (2025-01-01)

Dispersion of Activation in Single‐Beat Global Maps During Programmed Ventricular Stimulation Identifies Infarct‐Related Ventricular Tachycardia Isthmus Sites
by: Andrés Redondo‐Rodríguez, et al.
Published: (2024-12-01)

Advanced Imaging for Congenital Left Ventricular Diverticulum in a Dog: The Role of Electrocardiosynchronous CT
by: Miki Hirose, et al.
Published: (2025-01-01)

Comparison of Left Ventricular Global Longitudinal Strain and Left Ventricular Ejection Fraction in Acute Respiratory Failure Patients Requiring Invasive Mechanical Ventilation
by: Zubair Bashir, et al.
Published: (2024-10-01)

HeartMate 3 upgrade and aortic root replacement for severe aortic insufficiency and ventricular fibrillation
by: Katlin T. Schmitz, MD, et al.
Published: (2025-05-01)

Case Report: Diverticulum of the left ventricular outflow tract: multimodal imaging
by: Qiqing Chen, et al.
Published: (2024-11-01)

Identifying Ventricular Dysfunction Indicators in Electrocardiograms via Artificial Intelligence-Driven Analysis
by: Hisaki Makimoto, et al.
Published: (2024-10-01)

Efeito do treinamento aquático no perfil lipídico e na hipertrofia ventricular esquerda de camundongos hiperlipidêmicos
by: Gerusa Dias Siqueira Vilela Terra, et al.
Published: (2013-10-01)

Zero-fluoroscopy approach for radiofrequency catheter ablation of left-sided, idiopathic ventricular arrhythmias – feasibility, efficacy, and safety evaluation
by: Dariusz Rodkiewicz, et al.
Published: (2024-08-01)

The Role of Echocardiography in the Diagnosis of Left Ventricular Noncompaction: Usefulness in a Resource‐Constrained Setting
by: Aba A. Folson, et al.
Published: (2024-12-01)