Enhanced therapeutic efficacy for glioblastoma immunotherapy with an oncolytic herpes simplex virus armed with anti-PD-1 antibody and IL-12

Glioblastoma is the most common and aggressive malignant brain tumor and has limited treatment options. Hence, innovative approaches are urgently needed. Oncolytic virus therapy is emerging as a promising modality for cancer treatment due to its tumor-specific targeting and immune-stimulatory proper...

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Bibliographic Details
Main Authors: Lei Wang, Xusha Zhou, Xiaoqing Chen, Yuanyuan Liu, Yue Huang, Yuan Cheng, Peigen Ren, Jing Zhao, Grace Guoying Zhou
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Molecular Therapy: Oncology
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Online Access:http://www.sciencedirect.com/science/article/pii/S2950329924000419
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