Epstein-Barr virus (EBV) and systemic lupus erythematosus (SLE) association in serological studies

Over the past 50 years, a substantial body of research revealed an association between  Epstein-Barr virus (EBV), and various aspects of EBV infection, with multiple autoimmune diseases. Growing evidence points to EBV as a potential co-factor in systemic lupus erythematosus (SLE) and several mechan...

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Main Authors: Witold Czyż, Marta Chuncia-Ilczeko, Michalina Wójcikiewicz, Filip Arczewski, Karol Dziedzic, Julia Kulbacka, Maciej Wojszczyk, Damian Zys, Piotr Pasek, Julia Ryniecka
Format: Article
Language:English
Published: Nicolaus Copernicus University in Toruń 2025-01-01
Series:Quality in Sport
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Online Access:https://apcz.umk.pl/QS/article/view/57143
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author Witold Czyż
Marta Chuncia-Ilczeko
Michalina Wójcikiewicz
Filip Arczewski
Karol Dziedzic
Julia Kulbacka
Maciej Wojszczyk
Damian Zys
Piotr Pasek
Julia Ryniecka
author_facet Witold Czyż
Marta Chuncia-Ilczeko
Michalina Wójcikiewicz
Filip Arczewski
Karol Dziedzic
Julia Kulbacka
Maciej Wojszczyk
Damian Zys
Piotr Pasek
Julia Ryniecka
author_sort Witold Czyż
collection DOAJ
description Over the past 50 years, a substantial body of research revealed an association between  Epstein-Barr virus (EBV), and various aspects of EBV infection, with multiple autoimmune diseases. Growing evidence points to EBV as a potential co-factor in systemic lupus erythematosus (SLE) and several mechanisms have been proposed to explain this relationship, however there is as yet no conclusive proof of causality. This literature review constitutes an introduction into the subject and attempts to outline the findings on the EBV-SLE connection, focusing mostly on the evidence provided by serological studies.
format Article
id doaj-art-cd14851fc65e42c4b90dbfe6df27c3e5
institution Kabale University
issn 2450-3118
language English
publishDate 2025-01-01
publisher Nicolaus Copernicus University in Toruń
record_format Article
series Quality in Sport
spelling doaj-art-cd14851fc65e42c4b90dbfe6df27c3e52025-01-11T08:22:39ZengNicolaus Copernicus University in ToruńQuality in Sport2450-31182025-01-013710.12775/QS.2025.37.57143Epstein-Barr virus (EBV) and systemic lupus erythematosus (SLE) association in serological studiesWitold Czyż0https://orcid.org/0009-0006-4442-9900Marta Chuncia-Ilczeko1https://orcid.org/0009-0000-0913-9752Michalina Wójcikiewicz2https://orcid.org/0009-0003-3671-1410Filip Arczewski3https://orcid.org/0009-0008-5179-7255Karol Dziedzic4https://orcid.org/0009-0007-8317-723XJulia Kulbacka5https://orcid.org/0009-0005-1181-9104Maciej Wojszczyk6https://orcid.org/0009-0002-8668-8821Damian Zys7https://orcid.org/0009-0003-6578-6710Piotr Pasek8https://orcid.org/0009-0001-6218-9887Julia Ryniecka9https://orcid.org/0009-0000-5937-9498Centralny Szpital Kliniczny Uniwersytetu Medycznego w ŁodziCentral Teaching Hospital of the Medical University of Lodz, Pomorska 251, 92-213 Lodz, PolandCentral Teaching Hospital of the Medical University of Lodz, Pomorska 251, 92-213 Lodz, PolandMedical University of Lodz, Al T .Kosciuszki 4, 90-419 Lodz, PolandMedical University of Lodz, Al T .Kosciuszki 4, 90-419 Lodz, PolandCentral Teaching Hospital of the Medical University of Lodz, Pomorska 251, 92-213 Lodz, PolandUniversity Clinical Hospital No. 1 of the Medical University of Lodz, ul. Kopcińskiego 22, 90-153 Łódź University Clinical Hospital No. 1 of the Medical University of Lodz, ul. Kopcińskiego 22, 90-153 Łódź Copernicus Memorial Hospital, ul. Pabianicka 62, 93-513 Łódź, PolandMedical University of Lodz, Al T .Kosciuszki 4, 90-419 Lodz, Poland Over the past 50 years, a substantial body of research revealed an association between  Epstein-Barr virus (EBV), and various aspects of EBV infection, with multiple autoimmune diseases. Growing evidence points to EBV as a potential co-factor in systemic lupus erythematosus (SLE) and several mechanisms have been proposed to explain this relationship, however there is as yet no conclusive proof of causality. This literature review constitutes an introduction into the subject and attempts to outline the findings on the EBV-SLE connection, focusing mostly on the evidence provided by serological studies. https://apcz.umk.pl/QS/article/view/57143Epstein-Barr virusEBVSystemic lupus erythematosusSLEEBV seroprevalenceviral load
spellingShingle Witold Czyż
Marta Chuncia-Ilczeko
Michalina Wójcikiewicz
Filip Arczewski
Karol Dziedzic
Julia Kulbacka
Maciej Wojszczyk
Damian Zys
Piotr Pasek
Julia Ryniecka
Epstein-Barr virus (EBV) and systemic lupus erythematosus (SLE) association in serological studies
Quality in Sport
Epstein-Barr virus
EBV
Systemic lupus erythematosus
SLE
EBV seroprevalence
viral load
title Epstein-Barr virus (EBV) and systemic lupus erythematosus (SLE) association in serological studies
title_full Epstein-Barr virus (EBV) and systemic lupus erythematosus (SLE) association in serological studies
title_fullStr Epstein-Barr virus (EBV) and systemic lupus erythematosus (SLE) association in serological studies
title_full_unstemmed Epstein-Barr virus (EBV) and systemic lupus erythematosus (SLE) association in serological studies
title_short Epstein-Barr virus (EBV) and systemic lupus erythematosus (SLE) association in serological studies
title_sort epstein barr virus ebv and systemic lupus erythematosus sle association in serological studies
topic Epstein-Barr virus
EBV
Systemic lupus erythematosus
SLE
EBV seroprevalence
viral load
url https://apcz.umk.pl/QS/article/view/57143
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