Esketamine at a Clinical Dose Attenuates Cerebral Ischemia/Reperfusion Injury by Inhibiting AKT Signaling Pathway to Facilitate Microglia M2 Polarization and Autophagy

Esketamine at a Clinical Dose Attenuates Cerebral Ischemia/Reperfusion Injury by Inhibiting AKT Signaling Pathway to Facilitate Microglia M2 Polarization and Autophagy

Ying Gao,1 Lu Li,1 Fang Zhao,1 Yi Cheng,1 Mu Jin,2 Fu-Shan Xue1,3 1Department of Anesthesiology, Beijing Friendship Hospital, Capital Medical University, Beijing, People’s Republic of China; 2Department of Anesthesiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, People’s Republi...

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Bibliographic Details
Main Authors: Gao Y, Li L, Zhao F, Cheng Y, Jin M, Xue FS
Format: Article
Language:English
Published: Dove Medical Press 2025-01-01
Series:Drug Design, Development and Therapy
Subjects:
cerebral ischemia/reperfusion injury
esketamine
microglia polarization
autophagy
ischemic stroke
Online Access:https://www.dovepress.com/esketamine-at-a-clinical-dose-attenuates-cerebral-ischemiareperfusion--peer-reviewed-fulltext-article-DDDT
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