Role of circulating MicroRNAs in prostate cancer diagnosis and risk stratification in the MCC Spain study

Role of circulating MicroRNAs in prostate cancer diagnosis and risk stratification in the MCC Spain study

Abstract To identify circulating microRNAs (miRNAs) associated with prostate cancer and to develop predictive models capable of distinguishing cases from controls and stratifying patients by Gleason risk categories (low, intermediate, and high risk). This case-control study included 203 prostate can...

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Main Authors: Inés Gómez-Acebo, Sara Valero-Dominguez, Javier Llorca, Jessica Alonso-Molero, Thalía Belmonte, Gemma Castaño-Vinyals, Ana Molina-Barceló, Rafael Marcos-Gragera, Manolis Kogevinas, Paz Rodríguez-Cundín, Juan Alguacil, Beatriz Pérez-Gómez, Marina Pollán, Trinidad Dierssen-Sotos
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Prostate cancer
Gleason score
MiRNA
Diagnosis
Risk stratification
Online Access:https://doi.org/10.1038/s41598-025-01373-9
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