Molecularly imprinted biomimetic plasmonic sensor decorated with gold nanoparticles for selective and sensitive detection of bisphenol A
Molecularly imprinted polymers inspired by antigen-antibody interactions have received substantial interest as a biomimetic artificial receptor system in environmental applications. Herein, we present a molecularly imprinted surface plasmon resonance sensor integrated with gold nanoparticles for the...
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Elsevier
2024-12-01
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| Series: | Talanta Open |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666831924000936 |
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| author | Ilgım Göktürk Süleyman Aşır Deniz Türkmen Adil Denizli Fatma Yılmaz |
| author_facet | Ilgım Göktürk Süleyman Aşır Deniz Türkmen Adil Denizli Fatma Yılmaz |
| author_sort | Ilgım Göktürk |
| collection | DOAJ |
| description | Molecularly imprinted polymers inspired by antigen-antibody interactions have received substantial interest as a biomimetic artificial receptor system in environmental applications. Herein, we present a molecularly imprinted surface plasmon resonance sensor integrated with gold nanoparticles for the identification of bisphenol A (BPA), an endocrine-disrupting chemical. We synthesized BPA-imprinted nanofilm consisting of amino acid-based functional monomers to selectively detect BPA from synthetic wastewater samples. BPA-spiked synthetic wastewater samples were analyzed to ensure the method's reliability and feasibility. Under ideal conditions, the suggested approach performed well in terms of analytical performance to bisphenol A, with a wide linear range of 0.1 to 10 µg/L and LOD of 10 ng/L. The sensor results align well with the Langmuir adsorption model. It has also been shown that repeated use of the sensor can be achieved. According to selectivity studies, bisphenol A adsorbed within the imprinted cavities favorably compared to 4-nitrophenol and phenol. The produced bisphenol A-imprinted surface plasmon resonance sensor provides improved sensitivity based on the signal amplification strategy, unconjugated sensing without the need for labelling, real-time sensing, low sample consumption rates, quantifiable assessment, and outstanding kinetic rate constant calculation in actual samples. Also, because the produced sensor is reusable with relative standard deviations (RSD)<1.25, indicating the sensor's precision, the surface plasmon resonance-based biomimetic BPA sensor is simple to practice and a cost-effective option. |
| format | Article |
| id | doaj-art-ccd072436c3a43b0901ab6547a3e5a01 |
| institution | Kabale University |
| issn | 2666-8319 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Talanta Open |
| spelling | doaj-art-ccd072436c3a43b0901ab6547a3e5a012024-12-13T11:06:12ZengElsevierTalanta Open2666-83192024-12-0110100379Molecularly imprinted biomimetic plasmonic sensor decorated with gold nanoparticles for selective and sensitive detection of bisphenol AIlgım Göktürk0Süleyman Aşır1Deniz Türkmen2Adil Denizli3Fatma Yılmaz4Hacettepe University, Department of Chemistry, Beytepe, Ankara, TurkeyNear East University, Department of Biomedical Engineering, 99138, Nicosia, North Cyprus, Mersin 10, Turkey; Near East University, Research Center for Science, Technology and Engineering (BILTEM), 99138, Nicosia, North Cyprus, Mersin 10, TurkeyHacettepe University, Department of Chemistry, Beytepe, Ankara, TurkeyHacettepe University, Department of Chemistry, Beytepe, Ankara, TurkeyBolu Abant Izzet Baysal University, Chemistry Technology Division, Gerede, Bolu, Turkey; Corresponding author.Molecularly imprinted polymers inspired by antigen-antibody interactions have received substantial interest as a biomimetic artificial receptor system in environmental applications. Herein, we present a molecularly imprinted surface plasmon resonance sensor integrated with gold nanoparticles for the identification of bisphenol A (BPA), an endocrine-disrupting chemical. We synthesized BPA-imprinted nanofilm consisting of amino acid-based functional monomers to selectively detect BPA from synthetic wastewater samples. BPA-spiked synthetic wastewater samples were analyzed to ensure the method's reliability and feasibility. Under ideal conditions, the suggested approach performed well in terms of analytical performance to bisphenol A, with a wide linear range of 0.1 to 10 µg/L and LOD of 10 ng/L. The sensor results align well with the Langmuir adsorption model. It has also been shown that repeated use of the sensor can be achieved. According to selectivity studies, bisphenol A adsorbed within the imprinted cavities favorably compared to 4-nitrophenol and phenol. The produced bisphenol A-imprinted surface plasmon resonance sensor provides improved sensitivity based on the signal amplification strategy, unconjugated sensing without the need for labelling, real-time sensing, low sample consumption rates, quantifiable assessment, and outstanding kinetic rate constant calculation in actual samples. Also, because the produced sensor is reusable with relative standard deviations (RSD)<1.25, indicating the sensor's precision, the surface plasmon resonance-based biomimetic BPA sensor is simple to practice and a cost-effective option.http://www.sciencedirect.com/science/article/pii/S2666831924000936Molecularly imprinted polymersBisphenol AEndocrine-disrupting chemicalsGold nanoparticlesSensorSurface plasmon resonance |
| spellingShingle | Ilgım Göktürk Süleyman Aşır Deniz Türkmen Adil Denizli Fatma Yılmaz Molecularly imprinted biomimetic plasmonic sensor decorated with gold nanoparticles for selective and sensitive detection of bisphenol A Talanta Open Molecularly imprinted polymers Bisphenol A Endocrine-disrupting chemicals Gold nanoparticles Sensor Surface plasmon resonance |
| title | Molecularly imprinted biomimetic plasmonic sensor decorated with gold nanoparticles for selective and sensitive detection of bisphenol A |
| title_full | Molecularly imprinted biomimetic plasmonic sensor decorated with gold nanoparticles for selective and sensitive detection of bisphenol A |
| title_fullStr | Molecularly imprinted biomimetic plasmonic sensor decorated with gold nanoparticles for selective and sensitive detection of bisphenol A |
| title_full_unstemmed | Molecularly imprinted biomimetic plasmonic sensor decorated with gold nanoparticles for selective and sensitive detection of bisphenol A |
| title_short | Molecularly imprinted biomimetic plasmonic sensor decorated with gold nanoparticles for selective and sensitive detection of bisphenol A |
| title_sort | molecularly imprinted biomimetic plasmonic sensor decorated with gold nanoparticles for selective and sensitive detection of bisphenol a |
| topic | Molecularly imprinted polymers Bisphenol A Endocrine-disrupting chemicals Gold nanoparticles Sensor Surface plasmon resonance |
| url | http://www.sciencedirect.com/science/article/pii/S2666831924000936 |
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