Effect of omalizumab on inflammatory markers in COVID-19: an exploratory analysis of the COVID-19 immunologic antiviral therapy with omalizumab (CIAO) trial

Effect of omalizumab on inflammatory markers in COVID-19: an exploratory analysis of the COVID-19 immunologic antiviral therapy with omalizumab (CIAO) trial

BackgroundThe CIAO trial recently demonstrated a probable clinical benefit of omalizumab in the treatment of severe COVID-19; however, the mechanism underlying this benefit remains unclear. Therefore, we sought to longitudinally assess the impact of omalizumab on serum cytokines in CIAO trial patien...

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Bibliographic Details
Main Authors: Connor Prosty, Michelle Le, Yang Lu, Lauren Khoury, Maxime Cormier, Mathew P. Cheng, Robert Fowler, Srinivas Murthy, Jennifer LY Tsang, Duncan Lejtenyi, Moshe Ben-Shoshan, Elham Rahme, Shirin Golchi, Nandini Dendukuri, Todd C. Lee, Elena Netchiporouk
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Medicine
Subjects:
omalizumab
coronavirus
COVID-19
clinical trial
cytokine
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2024.1437322/full
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