<i>Clostridia</i> as Promising Biofactory for Heterotrophic (Fructose) and Autotrophic (C1-Gas) Fermentation

This study compared the performance of <i>Clostridium ljungdahlii</i> and <i>Clostridium aceticum</i> in the fermentation of fructose and C1-gasses (CO, CO<sub>2</sub>, N<sub>2</sub>) to produce valuable products such as ethanol and acetic acid. In het...

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Main Authors: Marina Fernández-Delgado, Mónica Coca, Susana Lucas, María Teresa García-Cubero, Juan Carlos López-Linares
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Fermentation
Subjects:
Online Access:https://www.mdpi.com/2311-5637/10/11/572
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author Marina Fernández-Delgado
Mónica Coca
Susana Lucas
María Teresa García-Cubero
Juan Carlos López-Linares
author_facet Marina Fernández-Delgado
Mónica Coca
Susana Lucas
María Teresa García-Cubero
Juan Carlos López-Linares
author_sort Marina Fernández-Delgado
collection DOAJ
description This study compared the performance of <i>Clostridium ljungdahlii</i> and <i>Clostridium aceticum</i> in the fermentation of fructose and C1-gasses (CO, CO<sub>2</sub>, N<sub>2</sub>) to produce valuable products such as ethanol and acetic acid. In heterotrophic fermentation (fructose), <i>C. ljungdahlii</i> yielded high ethanol concentrations (350 mg/L) and acetic acid (500 mg/L), with optimal production at pH 8 on the first day of fermentation. Although autotrophic fermentation (C1-gasses) resulted in lower ethanol levels (200 mg/L), it remained a viable option. Conversely, <i>C. aceticum</i> predominantly produced acetic acid in both fermentation modes, with higher concentrations in the heterotrophic fermentation (1600 mg/L) than the autotrophic fermentation (380 mg/L). These findings demonstrate the versatility of both microorganisms for producing valuable metabolites. <i>C. ljungdahlii</i> shows promise for bioethanol production, while <i>C. aceticum</i> excels at generating acetic acid, a crucial component in bioplastics and various industrial processes.
format Article
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institution Kabale University
issn 2311-5637
language English
publishDate 2024-11-01
publisher MDPI AG
record_format Article
series Fermentation
spelling doaj-art-cca3ba82b7774214976b0578acac54d02024-11-26T18:03:32ZengMDPI AGFermentation2311-56372024-11-01101157210.3390/fermentation10110572<i>Clostridia</i> as Promising Biofactory for Heterotrophic (Fructose) and Autotrophic (C1-Gas) FermentationMarina Fernández-Delgado0Mónica Coca1Susana Lucas2María Teresa García-Cubero3Juan Carlos López-Linares4Department of Chemical Engineering and Environmental Technology, University of Valladolid, Dr. Mergelina s/n, 47011 Valladolid, SpainDepartment of Chemical Engineering and Environmental Technology, University of Valladolid, Dr. Mergelina s/n, 47011 Valladolid, SpainDepartment of Chemical Engineering and Environmental Technology, University of Valladolid, Dr. Mergelina s/n, 47011 Valladolid, SpainDepartment of Chemical Engineering and Environmental Technology, University of Valladolid, Dr. Mergelina s/n, 47011 Valladolid, SpainDepartment of Chemical Engineering and Environmental Technology, University of Valladolid, Dr. Mergelina s/n, 47011 Valladolid, SpainThis study compared the performance of <i>Clostridium ljungdahlii</i> and <i>Clostridium aceticum</i> in the fermentation of fructose and C1-gasses (CO, CO<sub>2</sub>, N<sub>2</sub>) to produce valuable products such as ethanol and acetic acid. In heterotrophic fermentation (fructose), <i>C. ljungdahlii</i> yielded high ethanol concentrations (350 mg/L) and acetic acid (500 mg/L), with optimal production at pH 8 on the first day of fermentation. Although autotrophic fermentation (C1-gasses) resulted in lower ethanol levels (200 mg/L), it remained a viable option. Conversely, <i>C. aceticum</i> predominantly produced acetic acid in both fermentation modes, with higher concentrations in the heterotrophic fermentation (1600 mg/L) than the autotrophic fermentation (380 mg/L). These findings demonstrate the versatility of both microorganisms for producing valuable metabolites. <i>C. ljungdahlii</i> shows promise for bioethanol production, while <i>C. aceticum</i> excels at generating acetic acid, a crucial component in bioplastics and various industrial processes.https://www.mdpi.com/2311-5637/10/11/572C1-gassesWood–Ljungdahl pathwayethanolacetic acid<i>Clostridia</i> spp.
spellingShingle Marina Fernández-Delgado
Mónica Coca
Susana Lucas
María Teresa García-Cubero
Juan Carlos López-Linares
<i>Clostridia</i> as Promising Biofactory for Heterotrophic (Fructose) and Autotrophic (C1-Gas) Fermentation
Fermentation
C1-gasses
Wood–Ljungdahl pathway
ethanol
acetic acid
<i>Clostridia</i> spp.
title <i>Clostridia</i> as Promising Biofactory for Heterotrophic (Fructose) and Autotrophic (C1-Gas) Fermentation
title_full <i>Clostridia</i> as Promising Biofactory for Heterotrophic (Fructose) and Autotrophic (C1-Gas) Fermentation
title_fullStr <i>Clostridia</i> as Promising Biofactory for Heterotrophic (Fructose) and Autotrophic (C1-Gas) Fermentation
title_full_unstemmed <i>Clostridia</i> as Promising Biofactory for Heterotrophic (Fructose) and Autotrophic (C1-Gas) Fermentation
title_short <i>Clostridia</i> as Promising Biofactory for Heterotrophic (Fructose) and Autotrophic (C1-Gas) Fermentation
title_sort i clostridia i as promising biofactory for heterotrophic fructose and autotrophic c1 gas fermentation
topic C1-gasses
Wood–Ljungdahl pathway
ethanol
acetic acid
<i>Clostridia</i> spp.
url https://www.mdpi.com/2311-5637/10/11/572
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AT susanalucas iclostridiaiaspromisingbiofactoryforheterotrophicfructoseandautotrophicc1gasfermentation
AT mariateresagarciacubero iclostridiaiaspromisingbiofactoryforheterotrophicfructoseandautotrophicc1gasfermentation
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