NEAT1 regulates BMSCs aging through disruption of FGF2 nuclear transport

NEAT1 regulates BMSCs aging through disruption of FGF2 nuclear transport

Abstract Background The aging of bone marrow mesenchymal stem cells (BMSCs) impairs bone tissue regeneration, contributing to skeletal disorders. LncRNA NEAT1 is considered as a proliferative inhibitory role during cellular senescence, but the relevant mechanisms remain insufficient. This study aims...

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Main Authors: Zifei Wang, Wenyu Zhen, Qing Wang, Yuqiang Sun, Siyu Jin, Sensen Yu, Xing Wu, Wenhao Zhang, Yulong Zhang, Fei Xu, Rui Wang, Yuxuan Xie, Wansu Sun, Jianguang Xu, Hengguo Zhang
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Stem Cell Research & Therapy
Online Access:https://doi.org/10.1186/s13287-025-04156-1
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