HIF1A/BNIP3 pathway affects ferroptosis in sepsis-induced cardiomyopathy through binding to BCL-2

HIF1A/BNIP3 pathway affects ferroptosis in sepsis-induced cardiomyopathy through binding to BCL-2

Background: Sepsis-induced cardiomyopathy (SIC) involves ferroptosis, an iron-dependent cell death. Hypoxia-inducible factor-1α (HIF-1α) regulates autophagy and apoptosis, but its role in ferroptosis remains unclear. This study investigates the interaction between the HIF1A/BNIP3 signaling pathway a...

Full description

Saved in:
Bibliographic Details
Main Authors: Xiaoyue Wang, Jinze Li, Yixin Zhang, Ming huang, Pengqiang Yang, Tianwen Huang, Qinghong Cheng
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Redox Report
Subjects:
Sepsis-induced cardiomyopathy
myocardial injury
ferroptosis
HIF-1α/BNIP3
BECN1/SLC7A11/GPX4
BCL-2
Online Access:https://www.tandfonline.com/doi/10.1080/13510002.2025.2544412
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items