Glial fibrillary acidic protein in cerebrospinal fluid in humans is sensitive to various pre-analytical conditions: possible explanation and solution

Glial fibrillary acidic protein in cerebrospinal fluid in humans is sensitive to various pre-analytical conditions: possible explanation and solution

Although glial fibrillary acidic protein (GFAP) has potential as a biomarker in cerebrospinal fluid, it is rarely used in clinical diagnosis due to high variability, low reliability, and poor reproducibility of results. Cerebrospinal fluid (CSF) was collected from patients (n = 167) at two sites at...

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Bibliographic Details
Main Authors: Björn Evertsson, Ingela Nilsson Remahl, Max Albert Hietala, Anja Finn
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Neurology
Subjects:
CSF
GFAP
pre-analysis
microtube
reliability
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2025.1627405/full
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