Subchronic effects of HgCl2 on cognitive function and central inflammation in type 2 diabetic rats: involvement of BDNF and acetylcholinesterase

Subchronic effects of HgCl2 on cognitive function and central inflammation in type 2 diabetic rats: involvement of BDNF and acetylcholinesterase

IntroductionType 2 diabetes mellitus (T2DM) is a major global health concern frequently related with chronic low-grade inflammation and a spectrum of cognitive impairments, including deficits in learning and memory. Mercury chloride (HgCl2), a widespread environmental pollutant, is recognized for it...

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Bibliographic Details
Main Authors: Douae Benloughmari, Samir Bikri, Meriam El Aboubi, Fatima-Zahra Yassif, Youssef Aboussaleh
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Toxicology
Subjects:
type 2 diabetes
mercury chloride
neuroinflammation
learning and memory
BDNF
acetylcholinesterase
Online Access:https://www.frontiersin.org/articles/10.3389/ftox.2025.1610720/full
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