Lack of biochemical signalling in GelMA leads to polarity reversion in intestinal organoids independent from mechanoreciprocity

Lack of biochemical signalling in GelMA leads to polarity reversion in intestinal organoids independent from mechanoreciprocity

Xenogeneic tumour origin and batch-to-batch variability of Engelbreth-Holm-Swarm sarcoma tumour cell-derived hydrogels (Matrigel, Cultrex) limit the biomedical application of organoids in tissue engineering. The gelatin-methacryloyl (GelMA) hydrogels represent a defined, tunable, and GMP-friendly al...

Full description

Saved in:
Bibliographic Details
Main Authors: Lenie Vanhove, Thomas Van Gansbeke, Bert Devriendt, Ruben Van der Meeren, Ruslan I. Dmitriev, Irina A. Okkelman
Format: Article
Language:English
Published: SAGE Publishing 2025-06-01
Series:Journal of Tissue Engineering
Online Access:https://doi.org/10.1177/20417314251345000
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items