Expression of senescence-related CD161 promotes extranodal NK/T cell lymphoma by affecting T cell phenotype and cell cycle

Expression of senescence-related CD161 promotes extranodal NK/T cell lymphoma by affecting T cell phenotype and cell cycle

Abstract Purpose The intention of this work is to probe the role of senescence-related gene CD161 in extranodal NK/T cell lymphoma (ENKTL). Methods This study used H2O2 to establish three distinct in vitro oxidative stress aging models (NKL, SNT-8, and YT). Western blotting was employed to assess th...

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Bibliographic Details
Main Authors: Chengxun Jin, Xin Li, Chaohe Zhang
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Molecular Medicine
Subjects:
Extranodal NK/T-cell lymphoma (ENKTL)
Cell cycle
T cell phenotype
CD161
Senescence
Online Access:https://doi.org/10.1186/s10020-024-00969-7
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