The physiological function of α-ketoglutarate acid and its research advances in stomatology

α-ketoglutarate (AKG) is an essential intermediary metabolite of the tricarboxylic acid (TCA) cycle and amino acid metabolism. By participating in the generation of adenosine-triphosphate (ATP) and the biosynthesis of a variety of important amino acids and proteins, it is widely involved in a series...

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Main Authors: CHENG Chunan, HU Dandan, KANG Feiwu
Format: Article
Language:zho
Published: Editorial Office of Journal of Oral and Maxillofacial Surgery 2024-06-01
Series:Kouqiang hemian waike zazhi
Subjects:
Online Access:https://journal06.magtech.org.cn/Jweb_joms/EN/10.12439/kqhm.1005-4979.2024.03.011
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author CHENG Chunan
HU Dandan
KANG Feiwu
author_facet CHENG Chunan
HU Dandan
KANG Feiwu
author_sort CHENG Chunan
collection DOAJ
description α-ketoglutarate (AKG) is an essential intermediary metabolite of the tricarboxylic acid (TCA) cycle and amino acid metabolism. By participating in the generation of adenosine-triphosphate (ATP) and the biosynthesis of a variety of important amino acids and proteins, it is widely involved in a series of important physiological processes. Since there are few reports on the research of AKG in stomatology, this paper reviews the physiological function of AKG and its research advances in stomatology, which may lay a theoretical foundation for broadening the application of AKG in stomatology.
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publisher Editorial Office of Journal of Oral and Maxillofacial Surgery
record_format Article
series Kouqiang hemian waike zazhi
spelling doaj-art-cbe84da3e90d49d1a0b538c8952643c42025-08-25T06:11:05ZzhoEditorial Office of Journal of Oral and Maxillofacial SurgeryKouqiang hemian waike zazhi1005-49792024-06-0134323123310.12439/kqhm.1005-4979.2024.03.011The physiological function of α-ketoglutarate acid and its research advances in stomatologyCHENG Chunan0HU Dandan1KANG Feiwu2Shanghai Engineering Research Center of Tooth Restoration and Regeneration & Tongji Research Institute of Stomatology & Department of Oral and Maxillofacial Surgery, Stomatological Hospital and Dental School, Tongji University, Shanghai 200072, ChinaShanghai Engineering Research Center of Tooth Restoration and Regeneration & Tongji Research Institute of Stomatology & Department of Oral and Maxillofacial Surgery, Stomatological Hospital and Dental School, Tongji University, Shanghai 200072, ChinaShanghai Engineering Research Center of Tooth Restoration and Regeneration & Tongji Research Institute of Stomatology & Department of Oral and Maxillofacial Surgery, Stomatological Hospital and Dental School, Tongji University, Shanghai 200072, Chinaα-ketoglutarate (AKG) is an essential intermediary metabolite of the tricarboxylic acid (TCA) cycle and amino acid metabolism. By participating in the generation of adenosine-triphosphate (ATP) and the biosynthesis of a variety of important amino acids and proteins, it is widely involved in a series of important physiological processes. Since there are few reports on the research of AKG in stomatology, this paper reviews the physiological function of AKG and its research advances in stomatology, which may lay a theoretical foundation for broadening the application of AKG in stomatology.https://journal06.magtech.org.cn/Jweb_joms/EN/10.12439/kqhm.1005-4979.2024.03.011α-ketoglutaratebone metabolismepigeneticsimmune regulation
spellingShingle CHENG Chunan
HU Dandan
KANG Feiwu
The physiological function of α-ketoglutarate acid and its research advances in stomatology
Kouqiang hemian waike zazhi
α-ketoglutarate
bone metabolism
epigenetics
immune regulation
title The physiological function of α-ketoglutarate acid and its research advances in stomatology
title_full The physiological function of α-ketoglutarate acid and its research advances in stomatology
title_fullStr The physiological function of α-ketoglutarate acid and its research advances in stomatology
title_full_unstemmed The physiological function of α-ketoglutarate acid and its research advances in stomatology
title_short The physiological function of α-ketoglutarate acid and its research advances in stomatology
title_sort physiological function of α ketoglutarate acid and its research advances in stomatology
topic α-ketoglutarate
bone metabolism
epigenetics
immune regulation
url https://journal06.magtech.org.cn/Jweb_joms/EN/10.12439/kqhm.1005-4979.2024.03.011
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