Type 1 diabetes genetic risk score variation across ancestries using whole genome sequencing and array-based approaches

Type 1 diabetes genetic risk score variation across ancestries using whole genome sequencing and array-based approaches

Abstract A Type 1 Diabetes Genetic Risk Score (T1DGRS) aids diagnosis and prediction of Type 1 Diabetes (T1D). While traditionally derived from imputed array genotypes, Whole Genome Sequencing (WGS) provides a more direct approach and is now increasingly used in clinical and research studies. We inv...

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Bibliographic Details
Main Authors: Ankit M. Arni, Diane P. Fraser, Seth A. Sharp, Richard A. Oram, Matthew B. Johnson, Michael N. Weedon, Kashyap A. Patel
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-82278-x
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