Integrative transcriptomics and metabolomics reveal neuroendocrine-lipid crosstalk and adenosine signaling in broiler under heat stress

Integrative transcriptomics and metabolomics reveal neuroendocrine-lipid crosstalk and adenosine signaling in broiler under heat stress

Abstract Background Heat stress (HS) is a significant challenge in poultry, negatively impacting feed efficiency and survival. These adaptive responses could lead to disrupted lipid metabolism, impaired immunity, and neural damage. We hypothesized that the neuroendocrine system plays a central role...

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Bibliographic Details
Main Authors: Bingxing An, Peihao Liu, Zhirui Yang, Fan Ying, Dawei Liu, Jie Wen, Guiping Zhao
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Genomics
Subjects:
Biomarkers
Heat stress
Metabolomics and transcriptomics
Neuroendocrine regulation
Online Access:https://doi.org/10.1186/s12864-025-11881-7
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