Do domain-specific protein language models outperform general models on immunology-related tasks?

Do domain-specific protein language models outperform general models on immunology-related tasks?

Deciphering the antigen recognition capabilities by T-cell and B-cell receptors (antibodies) is essential for advancing our understanding of adaptive immune system responses. In recent years, the development of protein language models (PLMs) has facilitated the development of bioinformatic pipelines...

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Bibliographic Details
Main Authors: Nicolas Deutschmann, Aurelien Pelissier, Anna Weber, Shuaijun Gao, Jasmina Bogojeska, María Rodríguez Martínez
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:ImmunoInformatics
Subjects:
Large Language Model
Protein Language Model
T cell
B cell
Evolution
Affinity
Online Access:http://www.sciencedirect.com/science/article/pii/S2667119024000065
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