P-27 OBESITY AND LIVER STEATOSIS IN ADOLESCENTS AND YOUNG ADULTS - RELATED FACTORS AND THE IMPACT OF LIFESTYLE
Conflict of interest: No Introduction and Objectives: Obesity and lifestyle are factors associated with steatotic liver disease related to metabolic dysfunction (MASLD). Objective: To describe the frequency of obesity and MASLD in adolescents/young adults and related factors. Patients / Materials an...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-12-01
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| Series: | Annals of Hepatology |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1665268124004241 |
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| author | Fabiana Martins Basilio Ana Carolina Cardoso Katia Bloch Nathalie Leite Cristiane Villela-Nogueira |
| author_facet | Fabiana Martins Basilio Ana Carolina Cardoso Katia Bloch Nathalie Leite Cristiane Villela-Nogueira |
| author_sort | Fabiana Martins Basilio |
| collection | DOAJ |
| description | Conflict of interest: No Introduction and Objectives: Obesity and lifestyle are factors associated with steatotic liver disease related to metabolic dysfunction (MASLD). Objective: To describe the frequency of obesity and MASLD in adolescents/young adults and related factors. Patients / Materials and Methods: Cross-sectional study. Demographic, anthropometric and lifestyle data were assessed (self-completed questionnaire). All underwent liver elastography with CAP (Fibroscan® Touch 502, Echosens, Fr) to estimate the frequency of steatosis (CAP ≥ 248 DB/m) and significant fibrosis (E > 7.9 kPa). The related factors for obesity and steatosis were assessed by logistic regression analysis. Results and Discussion: One hundred and twenty-three healthy individuals participated in the study (68.3% women, 19.5 ± 1.5 years). Pre-hypertension, overweight and obesity were identified in 13.3%, 16.3% and 10.6% respectively (62.8% were not satisfied with their weight). Alcohol consumption was 26.7% (2-4 drinks/week), higher in men. 6% had glycated hemoglobin ≥ 5.7% (Pre-diabetes) and 28% had hypercholesterolemia. Steatosis was identified in 21.1%, and no individual had significant fibrosis [median E = 4.4 (3.6 – 5.3) kPa]. The median daily time spent on the computer was 5 (3-8 hours), and 56% used the computer for more than 4 hours/day. The factors that were independently associated with obesity in these adolescents were pre-hypertension (OR 8.7: 95% CI 2.1-36.0, p=0.003) and time spent using a computer (OR 6.1: 1.09-34.9; p=0.039). Obesity (OR 71.4: 95%CI 7.0-725.5, p<0.001), pre-hypertension (OR 7.4: 95%CI 1.3-41.9, p=0.024) and male sex (OR 13.5: 95%CI 1.3-137.3, p=0.027) but not alcohol use was associated with the presence of hepatic steatosis. Conclusions: The prevalence of obesity, pre-hypertension and hepatic steatosis in adolescents/young adults is high. Lifestyle changes, including better control of screen time, must be implemented urgently in this population to combat obesity and steatosis. |
| format | Article |
| id | doaj-art-cb9d8e401cd74af8925bd6e5ce35034d |
| institution | Kabale University |
| issn | 1665-2681 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Annals of Hepatology |
| spelling | doaj-art-cb9d8e401cd74af8925bd6e5ce35034d2024-12-07T08:25:31ZengElsevierAnnals of Hepatology1665-26812024-12-0129101641P-27 OBESITY AND LIVER STEATOSIS IN ADOLESCENTS AND YOUNG ADULTS - RELATED FACTORS AND THE IMPACT OF LIFESTYLEFabiana Martins Basilio0Ana Carolina Cardoso1Katia Bloch2Nathalie Leite3Cristiane Villela-Nogueira4School of Medicine, Federal University of Rio de Janeiro, Brazil, RJ, BrasilHepatology Division, Clementino Fraga Filho University Hospital, Federal University of Rio de Janeiro, Brazil, RJ, BrasilPublic Health Institute, Federal University of Rio de Janeiro, Brazil, RJ, BrasilHepatology Division, Clementino Fraga Filho University Hospital, Federal University of Rio de Janeiro, Brazil, RJ, BrasilSchool of Medicine and Hepatology Division, Clementino Fraga Filho University Hospital, Federal University of Rio de Janeiro, Brazil, RJ, BrasilConflict of interest: No Introduction and Objectives: Obesity and lifestyle are factors associated with steatotic liver disease related to metabolic dysfunction (MASLD). Objective: To describe the frequency of obesity and MASLD in adolescents/young adults and related factors. Patients / Materials and Methods: Cross-sectional study. Demographic, anthropometric and lifestyle data were assessed (self-completed questionnaire). All underwent liver elastography with CAP (Fibroscan® Touch 502, Echosens, Fr) to estimate the frequency of steatosis (CAP ≥ 248 DB/m) and significant fibrosis (E > 7.9 kPa). The related factors for obesity and steatosis were assessed by logistic regression analysis. Results and Discussion: One hundred and twenty-three healthy individuals participated in the study (68.3% women, 19.5 ± 1.5 years). Pre-hypertension, overweight and obesity were identified in 13.3%, 16.3% and 10.6% respectively (62.8% were not satisfied with their weight). Alcohol consumption was 26.7% (2-4 drinks/week), higher in men. 6% had glycated hemoglobin ≥ 5.7% (Pre-diabetes) and 28% had hypercholesterolemia. Steatosis was identified in 21.1%, and no individual had significant fibrosis [median E = 4.4 (3.6 – 5.3) kPa]. The median daily time spent on the computer was 5 (3-8 hours), and 56% used the computer for more than 4 hours/day. The factors that were independently associated with obesity in these adolescents were pre-hypertension (OR 8.7: 95% CI 2.1-36.0, p=0.003) and time spent using a computer (OR 6.1: 1.09-34.9; p=0.039). Obesity (OR 71.4: 95%CI 7.0-725.5, p<0.001), pre-hypertension (OR 7.4: 95%CI 1.3-41.9, p=0.024) and male sex (OR 13.5: 95%CI 1.3-137.3, p=0.027) but not alcohol use was associated with the presence of hepatic steatosis. Conclusions: The prevalence of obesity, pre-hypertension and hepatic steatosis in adolescents/young adults is high. Lifestyle changes, including better control of screen time, must be implemented urgently in this population to combat obesity and steatosis.http://www.sciencedirect.com/science/article/pii/S1665268124004241 |
| spellingShingle | Fabiana Martins Basilio Ana Carolina Cardoso Katia Bloch Nathalie Leite Cristiane Villela-Nogueira P-27 OBESITY AND LIVER STEATOSIS IN ADOLESCENTS AND YOUNG ADULTS - RELATED FACTORS AND THE IMPACT OF LIFESTYLE Annals of Hepatology |
| title | P-27 OBESITY AND LIVER STEATOSIS IN ADOLESCENTS AND YOUNG ADULTS - RELATED FACTORS AND THE IMPACT OF LIFESTYLE |
| title_full | P-27 OBESITY AND LIVER STEATOSIS IN ADOLESCENTS AND YOUNG ADULTS - RELATED FACTORS AND THE IMPACT OF LIFESTYLE |
| title_fullStr | P-27 OBESITY AND LIVER STEATOSIS IN ADOLESCENTS AND YOUNG ADULTS - RELATED FACTORS AND THE IMPACT OF LIFESTYLE |
| title_full_unstemmed | P-27 OBESITY AND LIVER STEATOSIS IN ADOLESCENTS AND YOUNG ADULTS - RELATED FACTORS AND THE IMPACT OF LIFESTYLE |
| title_short | P-27 OBESITY AND LIVER STEATOSIS IN ADOLESCENTS AND YOUNG ADULTS - RELATED FACTORS AND THE IMPACT OF LIFESTYLE |
| title_sort | p 27 obesity and liver steatosis in adolescents and young adults related factors and the impact of lifestyle |
| url | http://www.sciencedirect.com/science/article/pii/S1665268124004241 |
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