A novel dual fixation method for improving the reliable assessment of pulmonary vascular morphology in pulmonary hypertension rats

A novel dual fixation method for improving the reliable assessment of pulmonary vascular morphology in pulmonary hypertension rats

Abstract This study introduced a novel dual fixation method for the pulmonary vasculature and lung tissue in pulmonary hypertension (PH) rats, addressing the limitations of traditional fixation methods that failed to accurately preserve the in vivo status of pulmonary vascular morphology. The modifi...

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Bibliographic Details
Main Authors: Yan Xu, Pu Liao, Xinyu Song, Wenchuan Guo, Bingxun Liu, Tong Ye, Ting Zhang, Rui Xiao, Liping Zhu, Yujun Shen, Yanjiang Xing, Jing Wang, Qinghua Hu
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Respiratory Research
Subjects:
Lung tissue fixation
Pulmonary hypertension
Pulmonary vascular morphology
Online Access:https://doi.org/10.1186/s12931-024-03091-8
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