Efficacy and safety of IDH inhibitors in IDH-mutated cancers: a systematic review and meta-analysis of 4 randomized controlled trials

Efficacy and safety of IDH inhibitors in IDH-mutated cancers: a systematic review and meta-analysis of 4 randomized controlled trials

Abstract Background Isocitrate dehydrogenase (IDH) inhibitors have shown great promise in the treatment of cancers with IDH mutations. There have been numerous clinical trials conducted on IDH inhibitors, and to evaluate their efficacy and safety, we aim to perform a meta-analysis. Methods To gather...

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Bibliographic Details
Main Authors: Zelin Cai, Huiting Yang, Zhuoran Yu, Jingyang Su, Jie Zhang, Zhifeng Ye, Keke Hu, Ting Huang, Heran Zhou
Format: Article
Language:English
Published: BMC 2024-11-01
Series:World Journal of Surgical Oncology
Subjects:
Isocitrate dehydrogenase
Safety
Efficacy
Inhibitor
Meta-analysis
Online Access:https://doi.org/10.1186/s12957-024-03579-z
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