Looking outside the box with a pathology aware AI approach for analyzing OCT retinal images in Stargardt disease

Looking outside the box with a pathology aware AI approach for analyzing OCT retinal images in Stargardt disease

Abstract Stargardt disease type 1 (STGD1) is a genetic disorder that leads to progressive vision loss, with no approved treatments currently available. The development of effective therapies faces the challenge of identifying appropriate outcome measures that accurately reflect treatment benefits. O...

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Bibliographic Details
Main Authors: Parisa Khateri, Tiana Koottungal, Damon Wong, Rupert W. Strauss, Lucas Janeschitz-Kriegl, Maximilian Pfau, Leopold Schmetterer, Hendrik P. N. Scholl
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
Subjects:
Stargardt Disease
Optical Coherence Tomography
Deep Learning
Retina Segmentation
Pathology-Aware Loss Function
Automated Image Analysis
Online Access:https://doi.org/10.1038/s41598-025-85213-w
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