Lipid accumulation in adipose tissue-resident iNKT cells contributes to an inflammatory phenotype

Lipid accumulation in adipose tissue-resident iNKT cells contributes to an inflammatory phenotype

Reciprocal communication between adipocytes and immune cells is essential to maintain optimal adipose tissue (AT) functionality. Amongst others, adipocytes directly interact with invariant NKT cells (iNKT cells), which in turn secrete various cytokines. A lipid-rich microenvironment, as observed in...

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Bibliographic Details
Main Authors: Imogen Morris, Frank Vrieling, Annemieke Bouwman, Rinke Stienstra, Eric Kalkhoven
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Adipocyte
Subjects:
iNKT cell
adipose tissue
lipids
lipid droplet
inflammation
Online Access:https://www.tandfonline.com/doi/10.1080/21623945.2024.2421750
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