AIMP1 exerts hearing protection role in age related hearing loss mice by regulating SIRT1 expression

Abstract Background Age related hearing loss (ARHL) is a sensorineural hearing disease caused by multiple factors and its pathogenesis is still unclear. This work aims to investigate the precise role of AIMP1 in ARHL. Methods HEI-OC1 cells were treated with 1 mM H2O2 for 2 h to induce cell damage. C...

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Bibliographic Details
Main Authors: Haisen Peng, Jiali Liu, Yuehui Liu, Chunhua Li, Zhilin Zhang, Shuihua Hu, Wen Xie
Format: Article
Language:English
Published: BMC 2025-08-01
Series:BMC Geriatrics
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Online Access:https://doi.org/10.1186/s12877-025-06237-5
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