Single-cell RNA sequencing and immune microenvironment analysis reveal PLOD2-driven malignant transformation in cervical cancer

Single-cell RNA sequencing and immune microenvironment analysis reveal PLOD2-driven malignant transformation in cervical cancer

BackgroundCervical cancer is the fourth most common cancer in women globally, and the main cause of the disease has been found to be ongoing HPV infection. Cervical cancer remains the primary cause of cancer-related death despite major improvements in screening and treatment approaches, especially i...

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Bibliographic Details
Main Authors: Zhiheng Lin, Fengxin Wang, Renwu Yin, Shengnan Li, Yuquan Bai, Baofang Zhang, Chenlin Sui, Hengjie Cao, Dune Su, Lianwei Xu, Honghong Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Immunology
Subjects:
cervical cancer
single-cell RNA sequencing
tumor microenvironment
prognostic model
immune evasion
therapeutic targets
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1522655/full
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