Methimazole-induced congenital hypothyroidism affects gonocytes differentiation and arrests meiosis: role of Sertoli cells

Methimazole-induced congenital hypothyroidism affects gonocytes differentiation and arrests meiosis: role of Sertoli cells

BackgroundCongenital hypothyroidism (CH) is a pathology that affects various organs, including the testicles. The mechanisms by which this condition alters fertility is unknown. This study aimed at determining if experimental CH affects gonocyte differentiation and arrests meiosis; and the possible...

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Main Authors: Andrea Gómez-Zúñiga, Daniel Adrián Landero-Huerta, Julio César Rojas-Castañeda, Karla Sánchez-Huerta, Itzel Jatziri Contreras-García, Rafael Reynoso-Robles, Marcela Arteaga-Silva, Rosa María Vigueras-Villaseñor
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
congenital hypothyroidism
Sertoli cells
gonocyte
meiosis
methimazole
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2024.1493872/full
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