Impaired ARID1A expression attenuated the immune response in gastric cancer via histone acetylation

Impaired ARID1A expression attenuated the immune response in gastric cancer via histone acetylation

Abstract Background The primary objective of this study was to examine whether ARID1A mutations confer a fitness advantage to gastric cancer from an immunological perspective, along with elucidating the underlying mechanism. Additionally, we aimed to identify the clinical potential of combining epig...

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Bibliographic Details
Main Authors: Yu Tang, Ruizhi Zhang, Gan Mao, Chong Li, Yisong Gao, Xuebing Zhou, Wenxiang Nie, Tianyu Song, Suao Liu, Kaixiong Tao, Peng Zhang, Wei Li
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Clinical Epigenetics
Subjects:
Gastric cancer
ARID1A
Epigenetics
Immune checkpoint inhibitor
Tumor immunity
Online Access:https://doi.org/10.1186/s13148-024-01805-9
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