Preclinical validation of anti‐nuclear factor‐kappa B therapy to inhibit human vestibular schwannoma growth

Preclinical validation of anti‐nuclear factor‐kappa B therapy to inhibit human vestibular schwannoma growth

Vestibular schwannomas (VSs), the most common tumors of the cerebellopontine angle, arise from Schwann cells lining the vestibular nerve. Pharmacotherapies against VS are almost non‐existent. Although the therapeutic inhibition of inflammatory modulators has been established for other neoplasms, it...

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Bibliographic Details
Main Authors: Sonam Dilwali, Martijn C. Briët, Shyan-Yuan Kao, Takeshi Fujita, Lukas D. Landegger, Michael P. Platt, Konstantina M. Stankovic
Format: Article
Language:English
Published: Wiley 2015-08-01
Series:Molecular Oncology
Subjects:
Vestibular schwannoma
Network analysis
NF-κB
TNF
BAY 11-7082
Curcumin
Online Access:https://doi.org/10.1016/j.molonc.2015.03.009
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https://doi.org/10.1016/j.molonc.2015.03.009

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