Global burden of kidney cancer attributable to smoking: A systematic analysis of the 1990–2021 global burden of disease study
Objective: This study aimed to evaluate the epidemiological burden and temporal trends of kidney cancer (KC) attributable to smoking from 1990 to 2021. Methods: The study included 204 countries and regions, as provided in the 2021 Global Burden of Disease (GBD) database. The study participants were...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-06-01
|
| Series: | Preventive Medicine Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211335525001354 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849328534815768576 |
|---|---|
| author | Dingtian Qi Bowen Wang Haoxun Zhang Feng Xiong Guoling Zhang Chunyang Wang |
| author_facet | Dingtian Qi Bowen Wang Haoxun Zhang Feng Xiong Guoling Zhang Chunyang Wang |
| author_sort | Dingtian Qi |
| collection | DOAJ |
| description | Objective: This study aimed to evaluate the epidemiological burden and temporal trends of kidney cancer (KC) attributable to smoking from 1990 to 2021. Methods: The study included 204 countries and regions, as provided in the 2021 Global Burden of Disease (GBD) database. The study participants were patients with KC attributable to smoking. The Deaths, Disability-Adjusted Life Years (DALYs), Years Lived with Disability (YLDs), and Years of Life Lost (YLLs) were estimated. Results: In 2021, KC attributable to smoking caused 16,216.48(95 % UI:9662.84 to 23,217.42) deaths globally, with DALYs at 382927.14(95 % UI:233634.99 to 536,755.44), YLDs at 16,084.01(95 % UI:9290.43 to 25,354.68), and YLLs at 366,843.12(95 % UI:223833.69 to 513,164.93). From 1990 to 2021, the age-standardized rate (ASR) of disease indicators has declined globally, and middle-sociodemographic index (SDI) countries demonstrated the most substantial increase in ASRs for all indicators. The global number of DALYs has increased, with the most substantial increases occurring in high-middle SDI countries. The effective difference (EF) for all four disease indicators generally exhibited a spiraling expanding trend with increasing SDI. Predictive analysis suggests that the number of indicators will increase from 2022 to 2040, whereas ASR for these indicators is expected to decline annually through 2040. Conclusions: The global burden of KC attributable to smoking remains substantial, particularly in high-SDI regions, especially among men. In recent years, Middle-SDI regions have exhibited the sharpest rise in disease burden, demanding continued focus. Addressing health outcomes solely through social development progress proves challenging,targeted strategies are essential. |
| format | Article |
| id | doaj-art-ca89eb9adf2a4d349de9da669a77c5d5 |
| institution | Kabale University |
| issn | 2211-3355 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Preventive Medicine Reports |
| spelling | doaj-art-ca89eb9adf2a4d349de9da669a77c5d52025-08-20T03:47:33ZengElsevierPreventive Medicine Reports2211-33552025-06-015410309610.1016/j.pmedr.2025.103096Global burden of kidney cancer attributable to smoking: A systematic analysis of the 1990–2021 global burden of disease studyDingtian Qi0Bowen Wang1Haoxun Zhang2Feng Xiong3Guoling Zhang4Chunyang Wang5The First Affiliated Hospital of Harbin Medical University, Harbin, ChinaThe First Affiliated Hospital of Harbin Medical University, Harbin, ChinaThe First Affiliated Hospital of Harbin Medical University, Harbin, ChinaThe First Affiliated Hospital of Harbin Medical University, Harbin, ChinaThe First Affiliated Hospital of Harbin Medical University, Harbin, ChinaCorresponding author at: Department of Urology, The First Affiliated Hospital of Harbin Medical University, Harbin, China.; The First Affiliated Hospital of Harbin Medical University, Harbin, ChinaObjective: This study aimed to evaluate the epidemiological burden and temporal trends of kidney cancer (KC) attributable to smoking from 1990 to 2021. Methods: The study included 204 countries and regions, as provided in the 2021 Global Burden of Disease (GBD) database. The study participants were patients with KC attributable to smoking. The Deaths, Disability-Adjusted Life Years (DALYs), Years Lived with Disability (YLDs), and Years of Life Lost (YLLs) were estimated. Results: In 2021, KC attributable to smoking caused 16,216.48(95 % UI:9662.84 to 23,217.42) deaths globally, with DALYs at 382927.14(95 % UI:233634.99 to 536,755.44), YLDs at 16,084.01(95 % UI:9290.43 to 25,354.68), and YLLs at 366,843.12(95 % UI:223833.69 to 513,164.93). From 1990 to 2021, the age-standardized rate (ASR) of disease indicators has declined globally, and middle-sociodemographic index (SDI) countries demonstrated the most substantial increase in ASRs for all indicators. The global number of DALYs has increased, with the most substantial increases occurring in high-middle SDI countries. The effective difference (EF) for all four disease indicators generally exhibited a spiraling expanding trend with increasing SDI. Predictive analysis suggests that the number of indicators will increase from 2022 to 2040, whereas ASR for these indicators is expected to decline annually through 2040. Conclusions: The global burden of KC attributable to smoking remains substantial, particularly in high-SDI regions, especially among men. In recent years, Middle-SDI regions have exhibited the sharpest rise in disease burden, demanding continued focus. Addressing health outcomes solely through social development progress proves challenging,targeted strategies are essential.http://www.sciencedirect.com/science/article/pii/S2211335525001354Kidney cancerSmokingGlobal burden of diseaseSDI;DALYs |
| spellingShingle | Dingtian Qi Bowen Wang Haoxun Zhang Feng Xiong Guoling Zhang Chunyang Wang Global burden of kidney cancer attributable to smoking: A systematic analysis of the 1990–2021 global burden of disease study Preventive Medicine Reports Kidney cancer Smoking Global burden of disease SDI;DALYs |
| title | Global burden of kidney cancer attributable to smoking: A systematic analysis of the 1990–2021 global burden of disease study |
| title_full | Global burden of kidney cancer attributable to smoking: A systematic analysis of the 1990–2021 global burden of disease study |
| title_fullStr | Global burden of kidney cancer attributable to smoking: A systematic analysis of the 1990–2021 global burden of disease study |
| title_full_unstemmed | Global burden of kidney cancer attributable to smoking: A systematic analysis of the 1990–2021 global burden of disease study |
| title_short | Global burden of kidney cancer attributable to smoking: A systematic analysis of the 1990–2021 global burden of disease study |
| title_sort | global burden of kidney cancer attributable to smoking a systematic analysis of the 1990 2021 global burden of disease study |
| topic | Kidney cancer Smoking Global burden of disease SDI;DALYs |
| url | http://www.sciencedirect.com/science/article/pii/S2211335525001354 |
| work_keys_str_mv | AT dingtianqi globalburdenofkidneycancerattributabletosmokingasystematicanalysisofthe19902021globalburdenofdiseasestudy AT bowenwang globalburdenofkidneycancerattributabletosmokingasystematicanalysisofthe19902021globalburdenofdiseasestudy AT haoxunzhang globalburdenofkidneycancerattributabletosmokingasystematicanalysisofthe19902021globalburdenofdiseasestudy AT fengxiong globalburdenofkidneycancerattributabletosmokingasystematicanalysisofthe19902021globalburdenofdiseasestudy AT guolingzhang globalburdenofkidneycancerattributabletosmokingasystematicanalysisofthe19902021globalburdenofdiseasestudy AT chunyangwang globalburdenofkidneycancerattributabletosmokingasystematicanalysisofthe19902021globalburdenofdiseasestudy |