Use of the Hyperbaric Chamber Versus Conventional Treatment for the Prevention of Amputation in Chronic Diabetic Foot and the Influence on Fitting and Rehabilitation: A Systematic Review
Diabetes mellitus (DM) is one of the most common chronic endocrine diseases, characterized by hyperglycemia, due to abnormal nitric oxide synthesis. The trend of an increase in the number of patients with DM continues. The medical and economic burden of DM is not only associated with hyperglycemia m...
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| Format: | Article |
| Language: | English |
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Wiley
2024-01-01
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| Series: | International Journal of Vascular Medicine |
| Online Access: | http://dx.doi.org/10.1155/ijvm/8450783 |
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| author | María Dolores Apolo-Arenas Laura Guerrero-Nogales César Luis Díaz-Muñoz Berta Caro-Puértolas José Alberto Parraca Alejandro Caña-Pino |
| author_facet | María Dolores Apolo-Arenas Laura Guerrero-Nogales César Luis Díaz-Muñoz Berta Caro-Puértolas José Alberto Parraca Alejandro Caña-Pino |
| author_sort | María Dolores Apolo-Arenas |
| collection | DOAJ |
| description | Diabetes mellitus (DM) is one of the most common chronic endocrine diseases, characterized by hyperglycemia, due to abnormal nitric oxide synthesis. The trend of an increase in the number of patients with DM continues. The medical and economic burden of DM is not only associated with hyperglycemia management but also with the management of DM-related complications. Most chronic DM–associated complications are vascular in nature. Thus, hyperbaric oxygen therapy (HBOT) can be used for primary and/or secondary prevention of vascular complications. This systematic review is aimed at providing an up-to-date analysis of the effects of HBOT in patients with diabetic foot ulcers (DFUs) on the prevention of amputation, fitting, and rehabilitation of amputees. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were followed to conduct this systematic review. PubMed and Web of Science (WOS) database were employed in the search, which ended in November 2023. A risk of bias analysis was performed using the Evidence Project tool. After analyzing the records obtained, 10 studies were identified. However, seven fulfilled the inclusion criteria and were included in this systematic review. All included patients were over 18 years of age and had DM. The degree of DFU was assessed with the Wagner scale, being between 2 and 4, and the age of previous treatment of these DFU was taken into account. The results of the current systematic review showed that significant improvements can be achieved with HBOT when comparing its effects to those of the control group that followed usual care. Most studies included in the review showed positive results for DFU, amputation prevention, fitting, and rehabilitation of amputees. Therefore, the use of a hyperbaric chamber and standard care, as opposed to standard care alone, is favorable in patients with chronic DFUs. Promising and positive results were achieved for wound healing in DFU and the prevention of amputations. |
| format | Article |
| id | doaj-art-ca294982e32c476d9318683db673b362 |
| institution | Kabale University |
| issn | 2090-2832 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Vascular Medicine |
| spelling | doaj-art-ca294982e32c476d9318683db673b3622025-01-07T00:00:01ZengWileyInternational Journal of Vascular Medicine2090-28322024-01-01202410.1155/ijvm/8450783Use of the Hyperbaric Chamber Versus Conventional Treatment for the Prevention of Amputation in Chronic Diabetic Foot and the Influence on Fitting and Rehabilitation: A Systematic ReviewMaría Dolores Apolo-Arenas0Laura Guerrero-Nogales1César Luis Díaz-Muñoz2Berta Caro-Puértolas3José Alberto Parraca4Alejandro Caña-Pino5Department of Medical-Surgical TherapyDepartment of Medical-Surgical TherapyDepartment of Medical-Surgical TherapyDepartment of Medical-Surgical TherapyDepartment of Sport and HealthDepartment of Medical-Surgical TherapyDiabetes mellitus (DM) is one of the most common chronic endocrine diseases, characterized by hyperglycemia, due to abnormal nitric oxide synthesis. The trend of an increase in the number of patients with DM continues. The medical and economic burden of DM is not only associated with hyperglycemia management but also with the management of DM-related complications. Most chronic DM–associated complications are vascular in nature. Thus, hyperbaric oxygen therapy (HBOT) can be used for primary and/or secondary prevention of vascular complications. This systematic review is aimed at providing an up-to-date analysis of the effects of HBOT in patients with diabetic foot ulcers (DFUs) on the prevention of amputation, fitting, and rehabilitation of amputees. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were followed to conduct this systematic review. PubMed and Web of Science (WOS) database were employed in the search, which ended in November 2023. A risk of bias analysis was performed using the Evidence Project tool. After analyzing the records obtained, 10 studies were identified. However, seven fulfilled the inclusion criteria and were included in this systematic review. All included patients were over 18 years of age and had DM. The degree of DFU was assessed with the Wagner scale, being between 2 and 4, and the age of previous treatment of these DFU was taken into account. The results of the current systematic review showed that significant improvements can be achieved with HBOT when comparing its effects to those of the control group that followed usual care. Most studies included in the review showed positive results for DFU, amputation prevention, fitting, and rehabilitation of amputees. Therefore, the use of a hyperbaric chamber and standard care, as opposed to standard care alone, is favorable in patients with chronic DFUs. Promising and positive results were achieved for wound healing in DFU and the prevention of amputations.http://dx.doi.org/10.1155/ijvm/8450783 |
| spellingShingle | María Dolores Apolo-Arenas Laura Guerrero-Nogales César Luis Díaz-Muñoz Berta Caro-Puértolas José Alberto Parraca Alejandro Caña-Pino Use of the Hyperbaric Chamber Versus Conventional Treatment for the Prevention of Amputation in Chronic Diabetic Foot and the Influence on Fitting and Rehabilitation: A Systematic Review International Journal of Vascular Medicine |
| title | Use of the Hyperbaric Chamber Versus Conventional Treatment for the Prevention of Amputation in Chronic Diabetic Foot and the Influence on Fitting and Rehabilitation: A Systematic Review |
| title_full | Use of the Hyperbaric Chamber Versus Conventional Treatment for the Prevention of Amputation in Chronic Diabetic Foot and the Influence on Fitting and Rehabilitation: A Systematic Review |
| title_fullStr | Use of the Hyperbaric Chamber Versus Conventional Treatment for the Prevention of Amputation in Chronic Diabetic Foot and the Influence on Fitting and Rehabilitation: A Systematic Review |
| title_full_unstemmed | Use of the Hyperbaric Chamber Versus Conventional Treatment for the Prevention of Amputation in Chronic Diabetic Foot and the Influence on Fitting and Rehabilitation: A Systematic Review |
| title_short | Use of the Hyperbaric Chamber Versus Conventional Treatment for the Prevention of Amputation in Chronic Diabetic Foot and the Influence on Fitting and Rehabilitation: A Systematic Review |
| title_sort | use of the hyperbaric chamber versus conventional treatment for the prevention of amputation in chronic diabetic foot and the influence on fitting and rehabilitation a systematic review |
| url | http://dx.doi.org/10.1155/ijvm/8450783 |
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