Lack of Lloviu Virus Disease Development in Ferret Model
The first isolate of the emerging filovirus Lloviu virus (LLOV) was obtained in 2022. No animal disease models have been established. We assessed the pathogenic potential of LLOV in ferrets after intranasal, intramuscular, or aerosol exposure. The lack of disease development shows ferrets are not a...
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| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Centers for Disease Control and Prevention
2024-12-01
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| Series: | Emerging Infectious Diseases |
| Online Access: | https://wwwnc.cdc.gov/eid/article/30/12/24-0818_article |
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| _version_ | 1846151354358169600 |
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| author | Paige Fletcher Kyle L. O’Donnell Joseph F. Rhoderick Corey W. Henderson Atsushi Okumura Trenton Bushmaker Ayato Takada Chad S. Clancy Gábor Kemenesi Andrea Marzi |
| author_facet | Paige Fletcher Kyle L. O’Donnell Joseph F. Rhoderick Corey W. Henderson Atsushi Okumura Trenton Bushmaker Ayato Takada Chad S. Clancy Gábor Kemenesi Andrea Marzi |
| author_sort | Paige Fletcher |
| collection | DOAJ |
| description |
The first isolate of the emerging filovirus Lloviu virus (LLOV) was obtained in 2022. No animal disease models have been established. We assessed the pathogenic potential of LLOV in ferrets after intranasal, intramuscular, or aerosol exposure. The lack of disease development shows ferrets are not a disease model for LLOV.
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| format | Article |
| id | doaj-art-ca0d073039ea46ca99e0cd7f8b51be74 |
| institution | Kabale University |
| issn | 1080-6040 1080-6059 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Centers for Disease Control and Prevention |
| record_format | Article |
| series | Emerging Infectious Diseases |
| spelling | doaj-art-ca0d073039ea46ca99e0cd7f8b51be742024-11-27T13:59:50ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592024-12-0130122639264210.3201/eid3012.240818Lack of Lloviu Virus Disease Development in Ferret ModelPaige FletcherKyle L. O’DonnellJoseph F. RhoderickCorey W. HendersonAtsushi OkumuraTrenton BushmakerAyato TakadaChad S. ClancyGábor KemenesiAndrea Marzi The first isolate of the emerging filovirus Lloviu virus (LLOV) was obtained in 2022. No animal disease models have been established. We assessed the pathogenic potential of LLOV in ferrets after intranasal, intramuscular, or aerosol exposure. The lack of disease development shows ferrets are not a disease model for LLOV. https://wwwnc.cdc.gov/eid/article/30/12/24-0818_article |
| spellingShingle | Paige Fletcher Kyle L. O’Donnell Joseph F. Rhoderick Corey W. Henderson Atsushi Okumura Trenton Bushmaker Ayato Takada Chad S. Clancy Gábor Kemenesi Andrea Marzi Lack of Lloviu Virus Disease Development in Ferret Model Emerging Infectious Diseases |
| title | Lack of Lloviu Virus Disease Development in Ferret Model |
| title_full | Lack of Lloviu Virus Disease Development in Ferret Model |
| title_fullStr | Lack of Lloviu Virus Disease Development in Ferret Model |
| title_full_unstemmed | Lack of Lloviu Virus Disease Development in Ferret Model |
| title_short | Lack of Lloviu Virus Disease Development in Ferret Model |
| title_sort | lack of lloviu virus disease development in ferret model |
| url | https://wwwnc.cdc.gov/eid/article/30/12/24-0818_article |
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