Association of ABO blood group with plasmodium falciparum malaria in Sudanese population

Background & Aims: Malaria is a febrile illness with an incubation period of one week or more. Plasmodium falciparum is responsible for the most severe forms. So, this cross-sectional hospital-based study conducted to determine the association between ABO blood group and Plasmodium falciparum in...

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Main Authors: Abdalla Mohamed, Mohammed Abdelmotalab, Mohamed Elbasheir
Format: Article
Language:English
Published: Urmia University of Medical Sciences 2024-11-01
Series:Journal of Research in Applied and Basic Medical Sciences
Subjects:
Online Access:http://ijrabms.umsu.ac.ir/article-1-314-en.pdf
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author Abdalla Mohamed
Mohammed Abdelmotalab
Mohamed Elbasheir
author_facet Abdalla Mohamed
Mohammed Abdelmotalab
Mohamed Elbasheir
author_sort Abdalla Mohamed
collection DOAJ
description Background & Aims: Malaria is a febrile illness with an incubation period of one week or more. Plasmodium falciparum is responsible for the most severe forms. So, this cross-sectional hospital-based study conducted to determine the association between ABO blood group and Plasmodium falciparum infection. Materials & Methods: The study was carried out in three different clinics: Rota Clinic, Military Hospital, and Bahri Hospital in Khartoum states, Sudan. The study was conducted from May to August 2017. The sample size investigated was 580 subjects, with 200 subjects found to have a positive malaria infection (80 females and 120 males). Result: The results of this study revealed an overall infection rate of 34.4%. The prevalence rates reported in Military Hospital, Bahri Hospital, and Rota Clinic were 37.1%, 34.7%, and 28.2%, respectively. The study results showed that the highest prevalence rate (60%) was among males, while rate in females was 40%. The highest prevalence rate (32%) was reported among the age group 16-30 years old, and the lowest rate (13%) was among the age group 1-15 years old. The investigation revealed that the highest prevalence rate (58%) was among the O blood group, and the lowest prevalence rate (8%) was among the AB blood group. High parasitemia was strictly confined to A and B and low parasitemia in O blood group. Conclusion: Although the results showed relation of the disease with blood group, sex, and age group, further research with more population is necessary to add more information about the role of ABO blood groups in Plasmodium falciparum malaria and to contribute to malaria prevention.
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spelling doaj-art-c9ee79feca6b49e6a3f5fa148df42b1f2024-11-30T04:46:05ZengUrmia University of Medical SciencesJournal of Research in Applied and Basic Medical Sciences2717-00982024-11-01104340346Association of ABO blood group with plasmodium falciparum malaria in Sudanese populationAbdalla Mohamed0Mohammed Abdelmotalab1Mohamed Elbasheir2 Faculty of Medical Laboratory Science-based , Alzaiem Alazhari University, Sudan Faculty of Medicine , International University of Africa , Sudan Faculty of Medical Laboratory Science-based , Alzaiem Alazhari University, Sudan Background & Aims: Malaria is a febrile illness with an incubation period of one week or more. Plasmodium falciparum is responsible for the most severe forms. So, this cross-sectional hospital-based study conducted to determine the association between ABO blood group and Plasmodium falciparum infection. Materials & Methods: The study was carried out in three different clinics: Rota Clinic, Military Hospital, and Bahri Hospital in Khartoum states, Sudan. The study was conducted from May to August 2017. The sample size investigated was 580 subjects, with 200 subjects found to have a positive malaria infection (80 females and 120 males). Result: The results of this study revealed an overall infection rate of 34.4%. The prevalence rates reported in Military Hospital, Bahri Hospital, and Rota Clinic were 37.1%, 34.7%, and 28.2%, respectively. The study results showed that the highest prevalence rate (60%) was among males, while rate in females was 40%. The highest prevalence rate (32%) was reported among the age group 16-30 years old, and the lowest rate (13%) was among the age group 1-15 years old. The investigation revealed that the highest prevalence rate (58%) was among the O blood group, and the lowest prevalence rate (8%) was among the AB blood group. High parasitemia was strictly confined to A and B and low parasitemia in O blood group. Conclusion: Although the results showed relation of the disease with blood group, sex, and age group, further research with more population is necessary to add more information about the role of ABO blood groups in Plasmodium falciparum malaria and to contribute to malaria prevention.http://ijrabms.umsu.ac.ir/article-1-314-en.pdfblood groupfalciparummalariaplasmodiumsudan
spellingShingle Abdalla Mohamed
Mohammed Abdelmotalab
Mohamed Elbasheir
Association of ABO blood group with plasmodium falciparum malaria in Sudanese population
Journal of Research in Applied and Basic Medical Sciences
blood group
falciparum
malaria
plasmodium
sudan
title Association of ABO blood group with plasmodium falciparum malaria in Sudanese population
title_full Association of ABO blood group with plasmodium falciparum malaria in Sudanese population
title_fullStr Association of ABO blood group with plasmodium falciparum malaria in Sudanese population
title_full_unstemmed Association of ABO blood group with plasmodium falciparum malaria in Sudanese population
title_short Association of ABO blood group with plasmodium falciparum malaria in Sudanese population
title_sort association of abo blood group with plasmodium falciparum malaria in sudanese population
topic blood group
falciparum
malaria
plasmodium
sudan
url http://ijrabms.umsu.ac.ir/article-1-314-en.pdf
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AT mohammedabdelmotalab associationofabobloodgroupwithplasmodiumfalciparummalariainsudanesepopulation
AT mohamedelbasheir associationofabobloodgroupwithplasmodiumfalciparummalariainsudanesepopulation