Management of Alopecia and Onychomycosis in a Lupus Patient
The array of potential differential diagnoses of cutaneous lupus erythematosus (CLE) is extensive. Exclusion of infection is paramount, given the patient’s immunodeficient state. We report the case of a 33-year-old female patient who presented with pruritic erythematous papules across her upper extr...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer – Medknow Publications
2024-12-01
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| Series: | Biomolecular and Health Science Journal |
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| Online Access: | https://journals.lww.com/10.4103/bhsj.bhsj_17_24 |
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| author | Muzayyana Sakiinah Awalia Willy Sandhika Stefanus Gunawan Kandinata Katsuya Suzuki |
| author_facet | Muzayyana Sakiinah Awalia Willy Sandhika Stefanus Gunawan Kandinata Katsuya Suzuki |
| author_sort | Muzayyana Sakiinah |
| collection | DOAJ |
| description | The array of potential differential diagnoses of cutaneous lupus erythematosus (CLE) is extensive. Exclusion of infection is paramount, given the patient’s immunodeficient state. We report the case of a 33-year-old female patient who presented with pruritic erythematous papules across her upper extremities, originally presumed to be a drug eruption. Cutaneous xerosis and desquamation involving the hands were also noted, concomitant with diffuse hair loss and onychodystrophy. Potassium hydroxide and culture analysis from nail scrapings aligned with onychomycosis. Concurrently, histopathological assessment of the skin biopsy illustrated subacute CLE. Following the completion of the antifungal, mycophenolate mofetil was initiated, owing to suboptimal outcomes observed with the previous treatment modalities. The resolution of scaling on the scalp was concomitant with the emergence of new hair growth. Alopecia in lupus erythematosus patients mandates a thorough examination, owing to the extensive spectrum of its potential causes. Involvement of the nails mandates a rigorous exclusion of infections. |
| format | Article |
| id | doaj-art-c9dc7e9747574abf9a18b2f483643ca3 |
| institution | Kabale University |
| issn | 2620-8636 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Wolters Kluwer – Medknow Publications |
| record_format | Article |
| series | Biomolecular and Health Science Journal |
| spelling | doaj-art-c9dc7e9747574abf9a18b2f483643ca32025-01-07T05:16:20ZengWolters Kluwer – Medknow PublicationsBiomolecular and Health Science Journal2620-86362024-12-017215716210.4103/bhsj.bhsj_17_24Management of Alopecia and Onychomycosis in a Lupus PatientMuzayyana SakiinahAwaliaWilly SandhikaStefanus Gunawan KandinataKatsuya SuzukiThe array of potential differential diagnoses of cutaneous lupus erythematosus (CLE) is extensive. Exclusion of infection is paramount, given the patient’s immunodeficient state. We report the case of a 33-year-old female patient who presented with pruritic erythematous papules across her upper extremities, originally presumed to be a drug eruption. Cutaneous xerosis and desquamation involving the hands were also noted, concomitant with diffuse hair loss and onychodystrophy. Potassium hydroxide and culture analysis from nail scrapings aligned with onychomycosis. Concurrently, histopathological assessment of the skin biopsy illustrated subacute CLE. Following the completion of the antifungal, mycophenolate mofetil was initiated, owing to suboptimal outcomes observed with the previous treatment modalities. The resolution of scaling on the scalp was concomitant with the emergence of new hair growth. Alopecia in lupus erythematosus patients mandates a thorough examination, owing to the extensive spectrum of its potential causes. Involvement of the nails mandates a rigorous exclusion of infections.https://journals.lww.com/10.4103/bhsj.bhsj_17_24alopeciacutaneous lupus erythematosusdiseasemanagementonychomycosis |
| spellingShingle | Muzayyana Sakiinah Awalia Willy Sandhika Stefanus Gunawan Kandinata Katsuya Suzuki Management of Alopecia and Onychomycosis in a Lupus Patient Biomolecular and Health Science Journal alopecia cutaneous lupus erythematosus disease management onychomycosis |
| title | Management of Alopecia and Onychomycosis in a Lupus Patient |
| title_full | Management of Alopecia and Onychomycosis in a Lupus Patient |
| title_fullStr | Management of Alopecia and Onychomycosis in a Lupus Patient |
| title_full_unstemmed | Management of Alopecia and Onychomycosis in a Lupus Patient |
| title_short | Management of Alopecia and Onychomycosis in a Lupus Patient |
| title_sort | management of alopecia and onychomycosis in a lupus patient |
| topic | alopecia cutaneous lupus erythematosus disease management onychomycosis |
| url | https://journals.lww.com/10.4103/bhsj.bhsj_17_24 |
| work_keys_str_mv | AT muzayyanasakiinah managementofalopeciaandonychomycosisinalupuspatient AT awalia managementofalopeciaandonychomycosisinalupuspatient AT willysandhika managementofalopeciaandonychomycosisinalupuspatient AT stefanusgunawankandinata managementofalopeciaandonychomycosisinalupuspatient AT katsuyasuzuki managementofalopeciaandonychomycosisinalupuspatient |