Incidence and risk factors of acute kidney injury in redo cardiac surgery: a single center analysis
Abstract The incidence, risk factors and prognostic implications of acute kidney injury (AKI) in patients undergoing redo cardiac surgery are still poorly defined. We prospectively collected data on 394 consecutive redo patients between January 2011 and October 2020. Patients were divided into group...
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Nature Portfolio
2024-11-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-024-78990-3 |
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| author | Luca Salvatore De Santo Antonino Salvatore Rubino Antonio Pio Montella Caterina Golini Petrarcone Lucrezia Palmieri Denise Galbiati Antonio Pisano Marisa De Feo |
| author_facet | Luca Salvatore De Santo Antonino Salvatore Rubino Antonio Pio Montella Caterina Golini Petrarcone Lucrezia Palmieri Denise Galbiati Antonio Pisano Marisa De Feo |
| author_sort | Luca Salvatore De Santo |
| collection | DOAJ |
| description | Abstract The incidence, risk factors and prognostic implications of acute kidney injury (AKI) in patients undergoing redo cardiac surgery are still poorly defined. We prospectively collected data on 394 consecutive redo patients between January 2011 and October 2020. Patients were divided into groups according to the occurrence of different degrees of postoperative AKI (No AKI vs. Any AKI; No AKI-AKI 1 vs. AKI 2–3). The relationship between AKI and other major complications was also investigated. Postoperatively, AKI 1 occurred in 124 (31.5%), AKI 2 in 36 (9.1%) and AKI 3 in 64 (16.2%). Higher KDIGO classes were associated with increased in-hospital mortality: 5.3% among patients with no postoperative AKI and 8.9%, 13.9% and 64.1% in patients with AKI 1, 2 and 3, respectively (p < 0.001). Age, baseline hemoglobin, comorbidity, EuroSCORE II, operative time and transfusion during CPB proved to be significantly associated to the occurrence of AKI. Our study confirms the burden and prognostic role of AKI in a large, all comers, single center database of redo cardiac procedures. |
| format | Article |
| id | doaj-art-c9d8f9a025b74dadb13a565f09c3357a |
| institution | DOAJ |
| issn | 2045-2322 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Nature Portfolio |
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| series | Scientific Reports |
| spelling | doaj-art-c9d8f9a025b74dadb13a565f09c3357a2025-08-20T02:50:00ZengNature PortfolioScientific Reports2045-23222024-11-011411810.1038/s41598-024-78990-3Incidence and risk factors of acute kidney injury in redo cardiac surgery: a single center analysisLuca Salvatore De Santo0Antonino Salvatore Rubino1Antonio Pio Montella2Caterina Golini Petrarcone3Lucrezia Palmieri4Denise Galbiati5Antonio Pisano6Marisa De Feo7Department of Translational Medical Sciences, Monaldi Hospital, University of Campania “Luigi Vanvitelli”Department of Medicine and Surgery, University of Enna “Kore”Department of Translational Medical Sciences, Monaldi Hospital, University of Campania “Luigi Vanvitelli”Department of Translational Medical Sciences, Monaldi Hospital, University of Campania “Luigi Vanvitelli”Department of Translational Medical Sciences, Monaldi Hospital, University of Campania “Luigi Vanvitelli”Cardiovascular Department, Cardiac Surgery Unit of the IRCCS Humanitas Research HospitalCardiac Anesthesia and Intensive Care Unit, Monaldi HospitalDepartment of Translational Medical Sciences, Monaldi Hospital, University of Campania “Luigi Vanvitelli”Abstract The incidence, risk factors and prognostic implications of acute kidney injury (AKI) in patients undergoing redo cardiac surgery are still poorly defined. We prospectively collected data on 394 consecutive redo patients between January 2011 and October 2020. Patients were divided into groups according to the occurrence of different degrees of postoperative AKI (No AKI vs. Any AKI; No AKI-AKI 1 vs. AKI 2–3). The relationship between AKI and other major complications was also investigated. Postoperatively, AKI 1 occurred in 124 (31.5%), AKI 2 in 36 (9.1%) and AKI 3 in 64 (16.2%). Higher KDIGO classes were associated with increased in-hospital mortality: 5.3% among patients with no postoperative AKI and 8.9%, 13.9% and 64.1% in patients with AKI 1, 2 and 3, respectively (p < 0.001). Age, baseline hemoglobin, comorbidity, EuroSCORE II, operative time and transfusion during CPB proved to be significantly associated to the occurrence of AKI. Our study confirms the burden and prognostic role of AKI in a large, all comers, single center database of redo cardiac procedures.https://doi.org/10.1038/s41598-024-78990-3 |
| spellingShingle | Luca Salvatore De Santo Antonino Salvatore Rubino Antonio Pio Montella Caterina Golini Petrarcone Lucrezia Palmieri Denise Galbiati Antonio Pisano Marisa De Feo Incidence and risk factors of acute kidney injury in redo cardiac surgery: a single center analysis Scientific Reports |
| title | Incidence and risk factors of acute kidney injury in redo cardiac surgery: a single center analysis |
| title_full | Incidence and risk factors of acute kidney injury in redo cardiac surgery: a single center analysis |
| title_fullStr | Incidence and risk factors of acute kidney injury in redo cardiac surgery: a single center analysis |
| title_full_unstemmed | Incidence and risk factors of acute kidney injury in redo cardiac surgery: a single center analysis |
| title_short | Incidence and risk factors of acute kidney injury in redo cardiac surgery: a single center analysis |
| title_sort | incidence and risk factors of acute kidney injury in redo cardiac surgery a single center analysis |
| url | https://doi.org/10.1038/s41598-024-78990-3 |
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