Primary pleural serous carcinoma of mullerian origin—Report of a rare case

Mullerian tumor arising from pleura is a rare occurrence and under-reported in medical literature. We hereby present such a case in a 47 years old female who presented with pleural effusion. Pleural biopsy revealed a papillary tumor with mild-to-moderate nuclear atypia. Immunohistochemistry profile...

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Main Authors: Shilpi Modi, Deepa Goel
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-12-01
Series:Indian Journal of Pathology and Microbiology
Subjects:
Online Access:https://journals.lww.com/10.4103/ijpm.ijpm_114_23
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author Shilpi Modi
Deepa Goel
author_facet Shilpi Modi
Deepa Goel
author_sort Shilpi Modi
collection DOAJ
description Mullerian tumor arising from pleura is a rare occurrence and under-reported in medical literature. We hereby present such a case in a 47 years old female who presented with pleural effusion. Pleural biopsy revealed a papillary tumor with mild-to-moderate nuclear atypia. Immunohistochemistry profile with positivity for WT1, Pax8, ER, and PR together with negative mesothelial markers and ruling out primary in female genitalia led us to a diagnosis of primary pleural serous carcinoma of mullerian origin. The patient received paclitaxel and carboplatin chemotherapy and is disease-free till now after 2 years of follow-up.
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institution Kabale University
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publisher Wolters Kluwer Medknow Publications
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series Indian Journal of Pathology and Microbiology
spelling doaj-art-c9ce2188e88949329871b9f288a72a732025-01-10T10:26:41ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49290974-51302024-12-0167489089210.4103/ijpm.ijpm_114_23Primary pleural serous carcinoma of mullerian origin—Report of a rare caseShilpi ModiDeepa GoelMullerian tumor arising from pleura is a rare occurrence and under-reported in medical literature. We hereby present such a case in a 47 years old female who presented with pleural effusion. Pleural biopsy revealed a papillary tumor with mild-to-moderate nuclear atypia. Immunohistochemistry profile with positivity for WT1, Pax8, ER, and PR together with negative mesothelial markers and ruling out primary in female genitalia led us to a diagnosis of primary pleural serous carcinoma of mullerian origin. The patient received paclitaxel and carboplatin chemotherapy and is disease-free till now after 2 years of follow-up.https://journals.lww.com/10.4103/ijpm.ijpm_114_23mullerianpleuralserous
spellingShingle Shilpi Modi
Deepa Goel
Primary pleural serous carcinoma of mullerian origin—Report of a rare case
Indian Journal of Pathology and Microbiology
mullerian
pleural
serous
title Primary pleural serous carcinoma of mullerian origin—Report of a rare case
title_full Primary pleural serous carcinoma of mullerian origin—Report of a rare case
title_fullStr Primary pleural serous carcinoma of mullerian origin—Report of a rare case
title_full_unstemmed Primary pleural serous carcinoma of mullerian origin—Report of a rare case
title_short Primary pleural serous carcinoma of mullerian origin—Report of a rare case
title_sort primary pleural serous carcinoma of mullerian origin report of a rare case
topic mullerian
pleural
serous
url https://journals.lww.com/10.4103/ijpm.ijpm_114_23
work_keys_str_mv AT shilpimodi primarypleuralserouscarcinomaofmullerianoriginreportofararecase
AT deepagoel primarypleuralserouscarcinomaofmullerianoriginreportofararecase