Assessment of Soft Tissue Changes after Various Orthognathic Surgeries for Class III Correction of Cleft Lip and Cleft Palate Patients: A Systematic Review and Meta-Analysis

The study aimed to evaluate soft tissue changes resulting from orthognathic surgery, specifically LeFort osteotomy, and distraction osteogenesis, in individuals with cleft lip and palate (CLP) suffering from midface hypoplasia. Following PRISMA guidelines, eight papers met inclusion criteria, with s...

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Main Authors: B Kanagasabapathy, Shubham Sharma, Piyush Dua, Nikil K. Jain, V Preethi, Monika
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-12-01
Series:Journal of Pharmacy and Bioallied Sciences
Subjects:
Online Access:https://journals.lww.com/10.4103/jpbs.jpbs_967_24
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author B Kanagasabapathy
Shubham Sharma
Piyush Dua
Nikil K. Jain
V Preethi
Monika
author_facet B Kanagasabapathy
Shubham Sharma
Piyush Dua
Nikil K. Jain
V Preethi
Monika
author_sort B Kanagasabapathy
collection DOAJ
description The study aimed to evaluate soft tissue changes resulting from orthognathic surgery, specifically LeFort osteotomy, and distraction osteogenesis, in individuals with cleft lip and palate (CLP) suffering from midface hypoplasia. Following PRISMA guidelines, eight papers met inclusion criteria, with six providing quantitative data for meta-analysis. Notably, significant improvements were observed in both hard and soft tissues, particularly with horizontal maxillary advancement. Overall, orthognathic surgery positively influenced soft tissue profiles, especially the combination of LeFort osteotomy and sagittal split osteotomy. Moreover, maxillary distraction osteogenesis demonstrated superior soft tissue changes compared to LeFort I osteotomy alone, suggesting avenues for further research and potential enhancements.
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institution Kabale University
issn 0976-4879
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language English
publishDate 2024-12-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Journal of Pharmacy and Bioallied Sciences
spelling doaj-art-c9ab76994f794bcc94b470c195b1eff82025-01-12T14:04:37ZengWolters Kluwer Medknow PublicationsJournal of Pharmacy and Bioallied Sciences0976-48790975-74062024-12-0116Suppl 4S3096S309810.4103/jpbs.jpbs_967_24Assessment of Soft Tissue Changes after Various Orthognathic Surgeries for Class III Correction of Cleft Lip and Cleft Palate Patients: A Systematic Review and Meta-AnalysisB KanagasabapathyShubham SharmaPiyush DuaNikil K. JainV PreethiMonikaThe study aimed to evaluate soft tissue changes resulting from orthognathic surgery, specifically LeFort osteotomy, and distraction osteogenesis, in individuals with cleft lip and palate (CLP) suffering from midface hypoplasia. Following PRISMA guidelines, eight papers met inclusion criteria, with six providing quantitative data for meta-analysis. Notably, significant improvements were observed in both hard and soft tissues, particularly with horizontal maxillary advancement. Overall, orthognathic surgery positively influenced soft tissue profiles, especially the combination of LeFort osteotomy and sagittal split osteotomy. Moreover, maxillary distraction osteogenesis demonstrated superior soft tissue changes compared to LeFort I osteotomy alone, suggesting avenues for further research and potential enhancements.https://journals.lww.com/10.4103/jpbs.jpbs_967_24cleft lip and palatedistraction osteogenesismidface hypoplasiaorthognathic surgerysoft tissue changes
spellingShingle B Kanagasabapathy
Shubham Sharma
Piyush Dua
Nikil K. Jain
V Preethi
Monika
Assessment of Soft Tissue Changes after Various Orthognathic Surgeries for Class III Correction of Cleft Lip and Cleft Palate Patients: A Systematic Review and Meta-Analysis
Journal of Pharmacy and Bioallied Sciences
cleft lip and palate
distraction osteogenesis
midface hypoplasia
orthognathic surgery
soft tissue changes
title Assessment of Soft Tissue Changes after Various Orthognathic Surgeries for Class III Correction of Cleft Lip and Cleft Palate Patients: A Systematic Review and Meta-Analysis
title_full Assessment of Soft Tissue Changes after Various Orthognathic Surgeries for Class III Correction of Cleft Lip and Cleft Palate Patients: A Systematic Review and Meta-Analysis
title_fullStr Assessment of Soft Tissue Changes after Various Orthognathic Surgeries for Class III Correction of Cleft Lip and Cleft Palate Patients: A Systematic Review and Meta-Analysis
title_full_unstemmed Assessment of Soft Tissue Changes after Various Orthognathic Surgeries for Class III Correction of Cleft Lip and Cleft Palate Patients: A Systematic Review and Meta-Analysis
title_short Assessment of Soft Tissue Changes after Various Orthognathic Surgeries for Class III Correction of Cleft Lip and Cleft Palate Patients: A Systematic Review and Meta-Analysis
title_sort assessment of soft tissue changes after various orthognathic surgeries for class iii correction of cleft lip and cleft palate patients a systematic review and meta analysis
topic cleft lip and palate
distraction osteogenesis
midface hypoplasia
orthognathic surgery
soft tissue changes
url https://journals.lww.com/10.4103/jpbs.jpbs_967_24
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