High speed innovations in photoacoustic microscopy
Abstract Photoacoustic microscopy (PAM) is a key implementation of photoacoustic imaging (PAI). PAM merges rich optical contrast with deep acoustic detection, allowing for broad biomedical research and diverse clinical applications. Recent advancements in PAM technology have dramatically improved it...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2024-11-01
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| Series: | npj Imaging |
| Online Access: | https://doi.org/10.1038/s44303-024-00052-0 |
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| _version_ | 1846171696889856000 |
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| author | Xiaoyi Zhu Luca Menozzi Soon-Woo Cho Junjie Yao |
| author_facet | Xiaoyi Zhu Luca Menozzi Soon-Woo Cho Junjie Yao |
| author_sort | Xiaoyi Zhu |
| collection | DOAJ |
| description | Abstract Photoacoustic microscopy (PAM) is a key implementation of photoacoustic imaging (PAI). PAM merges rich optical contrast with deep acoustic detection, allowing for broad biomedical research and diverse clinical applications. Recent advancements in PAM technology have dramatically improved its imaging speed, enabling real-time observation of dynamic biological processes in vivo and motion-sensitive targets in situ, such as brain activities and placental development. This review introduces the engineering principles of high-speed PAM, focusing on various excitation and detection methods, each presenting unique benefits and challenges. Driven by these technological innovations, high-speed PAM has expanded its applications across fundamental, preclinical, and clinical fields. We highlight these notable applications, discuss ongoing technical challenges, and outline future directions for the development of high-speed PAM. |
| format | Article |
| id | doaj-art-c97497a0092a4e05980dd02f22cb6e05 |
| institution | Kabale University |
| issn | 2948-197X |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | npj Imaging |
| spelling | doaj-art-c97497a0092a4e05980dd02f22cb6e052024-11-10T12:38:57ZengNature Portfolionpj Imaging2948-197X2024-11-012111610.1038/s44303-024-00052-0High speed innovations in photoacoustic microscopyXiaoyi Zhu0Luca Menozzi1Soon-Woo Cho2Junjie Yao3Department of Biomedical Engineering, Duke UniversityDepartment of Biomedical Engineering, Duke UniversityDepartment of Biomedical Engineering, Duke UniversityDepartment of Biomedical Engineering, Duke UniversityAbstract Photoacoustic microscopy (PAM) is a key implementation of photoacoustic imaging (PAI). PAM merges rich optical contrast with deep acoustic detection, allowing for broad biomedical research and diverse clinical applications. Recent advancements in PAM technology have dramatically improved its imaging speed, enabling real-time observation of dynamic biological processes in vivo and motion-sensitive targets in situ, such as brain activities and placental development. This review introduces the engineering principles of high-speed PAM, focusing on various excitation and detection methods, each presenting unique benefits and challenges. Driven by these technological innovations, high-speed PAM has expanded its applications across fundamental, preclinical, and clinical fields. We highlight these notable applications, discuss ongoing technical challenges, and outline future directions for the development of high-speed PAM.https://doi.org/10.1038/s44303-024-00052-0 |
| spellingShingle | Xiaoyi Zhu Luca Menozzi Soon-Woo Cho Junjie Yao High speed innovations in photoacoustic microscopy npj Imaging |
| title | High speed innovations in photoacoustic microscopy |
| title_full | High speed innovations in photoacoustic microscopy |
| title_fullStr | High speed innovations in photoacoustic microscopy |
| title_full_unstemmed | High speed innovations in photoacoustic microscopy |
| title_short | High speed innovations in photoacoustic microscopy |
| title_sort | high speed innovations in photoacoustic microscopy |
| url | https://doi.org/10.1038/s44303-024-00052-0 |
| work_keys_str_mv | AT xiaoyizhu highspeedinnovationsinphotoacousticmicroscopy AT lucamenozzi highspeedinnovationsinphotoacousticmicroscopy AT soonwoocho highspeedinnovationsinphotoacousticmicroscopy AT junjieyao highspeedinnovationsinphotoacousticmicroscopy |