Effectiveness of non-pharmacological interventions to decrease fatigue in people living with HIV/AIDS: a protocol of systematic review and meta-analysis

Introduction Fatigue is a common symptom among people living with HIV (PLWH). It has a substantial adverse impact on functional status and the ability to conduct activities of daily living. Identifying effective strategies to prevent or reduce fatigue is significant to promote the quality of life of...

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Main Authors: Min Wang, Xueling Xiao, Honghong Wang, Nancy R Reynolds, Leorey Saligan, Yunxiao Lei
Format: Article
Language:English
Published: BMJ Publishing Group 2020-09-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/10/9/e040996.full
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author Min Wang
Xueling Xiao
Honghong Wang
Nancy R Reynolds
Leorey Saligan
Yunxiao Lei
author_facet Min Wang
Xueling Xiao
Honghong Wang
Nancy R Reynolds
Leorey Saligan
Yunxiao Lei
author_sort Min Wang
collection DOAJ
description Introduction Fatigue is a common symptom among people living with HIV (PLWH). It has a substantial adverse impact on functional status and the ability to conduct activities of daily living. Identifying effective strategies to prevent or reduce fatigue is significant to promote the quality of life of this vulnerable population. The purpose of this review is to synthesise the non-pharmacological evidence and assess the effects of interventions on reducing HIV-related fatigue among PLWH.Methods and analysis We will comprehensively search literature available up to 30 June 2020, in the following databases: PubMed, Embase, CINAHL, Cochrane Library, Web of Science and PsycINFO. The reference list of selected studies and relevant published reviews will also be screened to retrieve potential articles. Two reviewers will identify the eligible articles, extract data and identify the biases in the selected studies. Any disagreements will be referred to a third reviewer. We will qualitatively synthesise the evidence and pool data with meta-analysis according to the heterogeneity of different studies.Ethics and dissemination This systematic review will not raise any ethical issues since it is a secondary data collection and analysis. The results will inform effective strategies to reduce fatigue among PLWH. The final report will be published in a peer-reviewed journal and academic conferences.PROSPERO registration number CRD42020153715.
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spelling doaj-art-c968b77e533646029de6df9c8e1a05aa2025-01-09T06:40:08ZengBMJ Publishing GroupBMJ Open2044-60552020-09-0110910.1136/bmjopen-2020-040996Effectiveness of non-pharmacological interventions to decrease fatigue in people living with HIV/AIDS: a protocol of systematic review and meta-analysisMin Wang0Xueling Xiao1Honghong Wang2Nancy R Reynolds3Leorey Saligan4Yunxiao Lei5Key Lab of Visual Damage and Regeneration & Restoration of Chongqing, Chongqing, ChinaXiangya Nursing School, Central South University, Changsha, Hunan, ChinaXiangya Nursing School, Central South University, Changsha, Hunan, ChinaSchool of Nursing, Johns Hopkins University, Baltimore, Maryland, USANational Institute of Nursing Research, National Institutes of Health, Bethesda, Maryland, USA2 Obstetrics and Gynecology Nursing, School of Nursing, Wannan Medical College, Wuhu, Anhui, ChinaIntroduction Fatigue is a common symptom among people living with HIV (PLWH). It has a substantial adverse impact on functional status and the ability to conduct activities of daily living. Identifying effective strategies to prevent or reduce fatigue is significant to promote the quality of life of this vulnerable population. The purpose of this review is to synthesise the non-pharmacological evidence and assess the effects of interventions on reducing HIV-related fatigue among PLWH.Methods and analysis We will comprehensively search literature available up to 30 June 2020, in the following databases: PubMed, Embase, CINAHL, Cochrane Library, Web of Science and PsycINFO. The reference list of selected studies and relevant published reviews will also be screened to retrieve potential articles. Two reviewers will identify the eligible articles, extract data and identify the biases in the selected studies. Any disagreements will be referred to a third reviewer. We will qualitatively synthesise the evidence and pool data with meta-analysis according to the heterogeneity of different studies.Ethics and dissemination This systematic review will not raise any ethical issues since it is a secondary data collection and analysis. The results will inform effective strategies to reduce fatigue among PLWH. The final report will be published in a peer-reviewed journal and academic conferences.PROSPERO registration number CRD42020153715.https://bmjopen.bmj.com/content/10/9/e040996.full
spellingShingle Min Wang
Xueling Xiao
Honghong Wang
Nancy R Reynolds
Leorey Saligan
Yunxiao Lei
Effectiveness of non-pharmacological interventions to decrease fatigue in people living with HIV/AIDS: a protocol of systematic review and meta-analysis
BMJ Open
title Effectiveness of non-pharmacological interventions to decrease fatigue in people living with HIV/AIDS: a protocol of systematic review and meta-analysis
title_full Effectiveness of non-pharmacological interventions to decrease fatigue in people living with HIV/AIDS: a protocol of systematic review and meta-analysis
title_fullStr Effectiveness of non-pharmacological interventions to decrease fatigue in people living with HIV/AIDS: a protocol of systematic review and meta-analysis
title_full_unstemmed Effectiveness of non-pharmacological interventions to decrease fatigue in people living with HIV/AIDS: a protocol of systematic review and meta-analysis
title_short Effectiveness of non-pharmacological interventions to decrease fatigue in people living with HIV/AIDS: a protocol of systematic review and meta-analysis
title_sort effectiveness of non pharmacological interventions to decrease fatigue in people living with hiv aids a protocol of systematic review and meta analysis
url https://bmjopen.bmj.com/content/10/9/e040996.full
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