Efficacy and safety of exogenous surfactant therapy in patients under 12 months of age invasively ventilated for severe bronchiolitis (SURFABRON): protocol for a multicentre, randomised, double-blind, controlled, non-profit trial

Efficacy and safety of exogenous surfactant therapy in patients under 12 months of age invasively ventilated for severe bronchiolitis (SURFABRON): protocol for a multicentre, randomised, double-blind, controlled, non-profit trial

Introduction Some evidence indicates that exogenous surfactant therapy may be effective in infants with acute viral bronchiolitis, even though more confirmatory data are needed. To date, no large multicentre trials have evaluated the effectiveness and safety of exogenous surfactant in severe cases o...

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Main Authors: Marco Binotti, Giulia Genoni, Paolo Biban, Giorgio Conti, Andrea Michele Wolfler, Silvia Carlassara, Eloisa Gitto, Immacolata Rulli, Andrea Moscatelli, Camilla Micalizzi, Fabio Savron, Raffaella Sagredini, Fabio Caramelli, Monica Fae, Andrea Pettenazzo, Valentina Stritoni, Luigia D’Amato, Geremia Zito Marinosci, Edoardo Calderini, Stefano Scalia Catenacci, Alberto Berardi, Francesco Torcetta, Ezio Bonanomi, Daniele Bonacina, Giorgio Ivani, Pierantonio Santuz
Format: Article
Language:English
Published: BMJ Publishing Group 2020-10-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/10/10/e038780.full
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