Effects of corneal epithelial remodeling on corneal asphericity after FS-LASIK and Trans-PRK: A prospective study
Purpose: To observe the changes in corneal epithelial thickness after FS-LASIK and Trans-PRK surgery and to investigate the impact of corneal epithelial remodeling on Q-value and HOA. Methods: In this prospective cohort study, 50 patients (100 eyes) underwent FS-LASIK and 45 patients (90 eyes) under...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2025-01-01
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| Series: | Indian Journal of Ophthalmology |
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| Online Access: | https://journals.lww.com/10.4103/IJO.IJO_623_24 |
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| _version_ | 1841556822549331968 |
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| author | Mingyu Xu Fan Yang Emmanuel Eric Pazo Qiwei Li Zheng Yang Yue Huang Shaozhen Zhao |
| author_facet | Mingyu Xu Fan Yang Emmanuel Eric Pazo Qiwei Li Zheng Yang Yue Huang Shaozhen Zhao |
| author_sort | Mingyu Xu |
| collection | DOAJ |
| description | Purpose:
To observe the changes in corneal epithelial thickness after FS-LASIK and Trans-PRK surgery and to investigate the impact of corneal epithelial remodeling on Q-value and HOA.
Methods:
In this prospective cohort study, 50 patients (100 eyes) underwent FS-LASIK and 45 patients (90 eyes) underwent Trans-PRK. Anterior segment OCT was used to measure the corneal epithelial thickness in different corneal zones (central zone: 0–2 mm; paracentral zone: 2–5 mm; and mid-peripheral zone: 5–6 mm) preoperatively and postoperatively at 1 week, 1 month, 3 months, and 6 months. The correlation between △CET in the superior, nasal, inferior, and temporal region at 6 months postoperatively and △Q and △HOA was analyzed.
Results:
At 6 months postoperatively, the epithelial thickness increased in the central, paracentral, and mid-peripheral zones in FS-LASIK and Trans-PRK. Central epithelial thickness and different regions of the paracentral zone and mid-peripheral exhibited significant thickening (P < 0.001). In the para-central zone and mid-peripheral zone, the △CET in different regions after LASIK and Trans-PRK was positively correlated with △Q (P < 0.05) and △HOA (P < 0.05).
Conclusion:
After FS-LASIK and Trans-PRK, significant epithelial thickening was observed. Epithelial changes in different regions lead to different Q-values in different regions and have different effects on HOA. This has a certain guiding significance for the design of refractive surgery, and minimizing the increase of Q-value may improve the postoperative visual quality. |
| format | Article |
| id | doaj-art-c944d94a234540e7a0980270d920848f |
| institution | Kabale University |
| issn | 0301-4738 1998-3689 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Ophthalmology |
| spelling | doaj-art-c944d94a234540e7a0980270d920848f2025-01-07T06:27:42ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892025-01-0173113414010.4103/IJO.IJO_623_24Effects of corneal epithelial remodeling on corneal asphericity after FS-LASIK and Trans-PRK: A prospective studyMingyu XuFan YangEmmanuel Eric PazoQiwei LiZheng YangYue HuangShaozhen ZhaoPurpose: To observe the changes in corneal epithelial thickness after FS-LASIK and Trans-PRK surgery and to investigate the impact of corneal epithelial remodeling on Q-value and HOA. Methods: In this prospective cohort study, 50 patients (100 eyes) underwent FS-LASIK and 45 patients (90 eyes) underwent Trans-PRK. Anterior segment OCT was used to measure the corneal epithelial thickness in different corneal zones (central zone: 0–2 mm; paracentral zone: 2–5 mm; and mid-peripheral zone: 5–6 mm) preoperatively and postoperatively at 1 week, 1 month, 3 months, and 6 months. The correlation between △CET in the superior, nasal, inferior, and temporal region at 6 months postoperatively and △Q and △HOA was analyzed. Results: At 6 months postoperatively, the epithelial thickness increased in the central, paracentral, and mid-peripheral zones in FS-LASIK and Trans-PRK. Central epithelial thickness and different regions of the paracentral zone and mid-peripheral exhibited significant thickening (P < 0.001). In the para-central zone and mid-peripheral zone, the △CET in different regions after LASIK and Trans-PRK was positively correlated with △Q (P < 0.05) and △HOA (P < 0.05). Conclusion: After FS-LASIK and Trans-PRK, significant epithelial thickening was observed. Epithelial changes in different regions lead to different Q-values in different regions and have different effects on HOA. This has a certain guiding significance for the design of refractive surgery, and minimizing the increase of Q-value may improve the postoperative visual quality.https://journals.lww.com/10.4103/IJO.IJO_623_24corneal epithelial thicknessfs-lasiktrans-prkcorneal asphericity |
| spellingShingle | Mingyu Xu Fan Yang Emmanuel Eric Pazo Qiwei Li Zheng Yang Yue Huang Shaozhen Zhao Effects of corneal epithelial remodeling on corneal asphericity after FS-LASIK and Trans-PRK: A prospective study Indian Journal of Ophthalmology corneal epithelial thickness fs-lasik trans-prk corneal asphericity |
| title | Effects of corneal epithelial remodeling on corneal asphericity after FS-LASIK and Trans-PRK: A prospective study |
| title_full | Effects of corneal epithelial remodeling on corneal asphericity after FS-LASIK and Trans-PRK: A prospective study |
| title_fullStr | Effects of corneal epithelial remodeling on corneal asphericity after FS-LASIK and Trans-PRK: A prospective study |
| title_full_unstemmed | Effects of corneal epithelial remodeling on corneal asphericity after FS-LASIK and Trans-PRK: A prospective study |
| title_short | Effects of corneal epithelial remodeling on corneal asphericity after FS-LASIK and Trans-PRK: A prospective study |
| title_sort | effects of corneal epithelial remodeling on corneal asphericity after fs lasik and trans prk a prospective study |
| topic | corneal epithelial thickness fs-lasik trans-prk corneal asphericity |
| url | https://journals.lww.com/10.4103/IJO.IJO_623_24 |
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