Association of abruptio placentae with hypertension in pregnancy: Analysis of risk factors in Nigerian women
Abstract Objective The incidence of abruptio placentae complicating hypertensive diseases of pregnancy is high in Nigerian referral hospitals. We conducted a retrospective case‐control study to identify the socio‐demographic, behavioural, and clinical risk factors associated with abruptio placentae...
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| Format: | Article |
| Language: | English |
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Wiley
2024-12-01
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| Series: | Reproductive, Female and Child Health |
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| Online Access: | https://doi.org/10.1002/rfc2.82 |
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| author | Maradona Isikhuemen Lorretta Ntoimo Vivian Onoh Nosakhare Idiagbonya Michael Orhue Friday Okonofua |
| author_facet | Maradona Isikhuemen Lorretta Ntoimo Vivian Onoh Nosakhare Idiagbonya Michael Orhue Friday Okonofua |
| author_sort | Maradona Isikhuemen |
| collection | DOAJ |
| description | Abstract Objective The incidence of abruptio placentae complicating hypertensive diseases of pregnancy is high in Nigerian referral hospitals. We conducted a retrospective case‐control study to identify the socio‐demographic, behavioural, and clinical risk factors associated with abruptio placentae in women with hypertensive diseases of pregnancy. Methods The 41 cases of hypertensive diseases complicated by abruptio placentae identified in the records of the University of Benin Teaching Hospital over 2 years (January 2021–December 2022) were compared with 208 women (controls) who had hypertensive diseases without developing abruptio placentae. Multiple regression analysis was used to develop maximum likelihood estimates of the adjusted odds ratios and 95% confidence intervals to predict the likelihood of the association between the exposure factors and the risk of abruptio placentae. Results High blood pressure levels at presentation, when managed, can decrease the odds for abruptio placentae by 9% OR 0.91, CI:0.83–0.9, but smoking and alcohol intake were not significantly associated with abruptio placentae. A higher haemoglobin concentration decreased the likelihood of abruptio placentae by 60% OR 0.40, (CI 0.24– 0.68), while higher birth weight babies minimally decreased the odds for abruptio placentae, OR 1.01 (CI 0.08–12.49). Conclusion We conclude that abruptio placentae is most likely to complicate hypertensive diseases of pregnancy in Nigerian women when there are concurrent pregnancy anaemia and low birth weight babies, while higher blood pressure levels at presentation, when promptly managed, can reduce the risk of abruptio placentae. Efforts to address the concurrent management of anaemia associated with hypertensive diseases in pregnancy will most likely reduce the incidence of abruptio placentae in this population. |
| format | Article |
| id | doaj-art-c939c8e7505047e7b60bdc9925a95792 |
| institution | Kabale University |
| issn | 2768-7228 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Wiley |
| record_format | Article |
| series | Reproductive, Female and Child Health |
| spelling | doaj-art-c939c8e7505047e7b60bdc9925a957922024-12-27T05:00:27ZengWileyReproductive, Female and Child Health2768-72282024-12-0134n/an/a10.1002/rfc2.82Association of abruptio placentae with hypertension in pregnancy: Analysis of risk factors in Nigerian womenMaradona Isikhuemen0Lorretta Ntoimo1Vivian Onoh2Nosakhare Idiagbonya3Michael Orhue4Friday Okonofua5Department of Obstetrics and Gynaecology University of Benin Teaching Hospital Benin City Edo State NigeriaDepartment of Demography and Social Statistics Federal University Oye‐Ekiti Oye‐Ekiti NigeriaCentre of Excellence in Reproductive Health Innovation (CERHI) University of Benin Benin City NigeriaDepartment of Obstetrics and Gynaecology University of Benin Teaching Hospital Benin City Edo State NigeriaDepartment of Obstetrics and Gynaecology University of Benin Teaching Hospital Benin City Edo State NigeriaDepartment of Obstetrics and Gynaecology University of Benin Teaching Hospital Benin City Edo State NigeriaAbstract Objective The incidence of abruptio placentae complicating hypertensive diseases of pregnancy is high in Nigerian referral hospitals. We conducted a retrospective case‐control study to identify the socio‐demographic, behavioural, and clinical risk factors associated with abruptio placentae in women with hypertensive diseases of pregnancy. Methods The 41 cases of hypertensive diseases complicated by abruptio placentae identified in the records of the University of Benin Teaching Hospital over 2 years (January 2021–December 2022) were compared with 208 women (controls) who had hypertensive diseases without developing abruptio placentae. Multiple regression analysis was used to develop maximum likelihood estimates of the adjusted odds ratios and 95% confidence intervals to predict the likelihood of the association between the exposure factors and the risk of abruptio placentae. Results High blood pressure levels at presentation, when managed, can decrease the odds for abruptio placentae by 9% OR 0.91, CI:0.83–0.9, but smoking and alcohol intake were not significantly associated with abruptio placentae. A higher haemoglobin concentration decreased the likelihood of abruptio placentae by 60% OR 0.40, (CI 0.24– 0.68), while higher birth weight babies minimally decreased the odds for abruptio placentae, OR 1.01 (CI 0.08–12.49). Conclusion We conclude that abruptio placentae is most likely to complicate hypertensive diseases of pregnancy in Nigerian women when there are concurrent pregnancy anaemia and low birth weight babies, while higher blood pressure levels at presentation, when promptly managed, can reduce the risk of abruptio placentae. Efforts to address the concurrent management of anaemia associated with hypertensive diseases in pregnancy will most likely reduce the incidence of abruptio placentae in this population.https://doi.org/10.1002/rfc2.82abruptio placentahypertensive diseases of pregnancymaternal mortalityNigerian womenrisk factors |
| spellingShingle | Maradona Isikhuemen Lorretta Ntoimo Vivian Onoh Nosakhare Idiagbonya Michael Orhue Friday Okonofua Association of abruptio placentae with hypertension in pregnancy: Analysis of risk factors in Nigerian women Reproductive, Female and Child Health abruptio placenta hypertensive diseases of pregnancy maternal mortality Nigerian women risk factors |
| title | Association of abruptio placentae with hypertension in pregnancy: Analysis of risk factors in Nigerian women |
| title_full | Association of abruptio placentae with hypertension in pregnancy: Analysis of risk factors in Nigerian women |
| title_fullStr | Association of abruptio placentae with hypertension in pregnancy: Analysis of risk factors in Nigerian women |
| title_full_unstemmed | Association of abruptio placentae with hypertension in pregnancy: Analysis of risk factors in Nigerian women |
| title_short | Association of abruptio placentae with hypertension in pregnancy: Analysis of risk factors in Nigerian women |
| title_sort | association of abruptio placentae with hypertension in pregnancy analysis of risk factors in nigerian women |
| topic | abruptio placenta hypertensive diseases of pregnancy maternal mortality Nigerian women risk factors |
| url | https://doi.org/10.1002/rfc2.82 |
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