Cortical direction selectivity increases from the input to the output layers of visual cortex.
Sensitivity to motion direction is a feature of visual neurons that is essential for motion perception. Recent studies have suggested that direction selectivity is re-established at multiple stages throughout the visual hierarchy, which contradicts the traditional assumption that direction selectivi...
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| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2025-01-01
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| Series: | PLoS Biology |
| Online Access: | https://doi.org/10.1371/journal.pbio.3002947 |
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| _version_ | 1841533265158078464 |
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| author | Weifeng Dai Tian Wang Yang Li Yi Yang Yange Zhang Yujie Wu Tingting Zhou Hongbo Yu Liang Li Yizheng Wang Gang Wang Dajun Xing |
| author_facet | Weifeng Dai Tian Wang Yang Li Yi Yang Yange Zhang Yujie Wu Tingting Zhou Hongbo Yu Liang Li Yizheng Wang Gang Wang Dajun Xing |
| author_sort | Weifeng Dai |
| collection | DOAJ |
| description | Sensitivity to motion direction is a feature of visual neurons that is essential for motion perception. Recent studies have suggested that direction selectivity is re-established at multiple stages throughout the visual hierarchy, which contradicts the traditional assumption that direction selectivity in later stages largely derives from that in earlier stages. By recording laminar responses in areas 17 and 18 of anesthetized cats of both sexes, we aimed to understand how direction selectivity is processed and relayed across 2 successive stages: the input layers and the output layers within the early visual cortices. We found a strong relationship between the strength of direction selectivity in the output layers and the input layers, as well as the preservation of preferred directions across the input and output layers. Moreover, direction selectivity was enhanced in the output layers compared to the input layers, with the response strength maintained in the preferred direction but reduced in other directions and under blank stimuli. We identified a direction-tuned gain mechanism for interlaminar signal transmission, which likely originated from both feedforward connections across the input and output layers and recurrent connections within the output layers. This direction-tuned gain, coupled with nonlinearity, contributed to the enhanced direction selectivity in the output layers. Our findings suggest that direction selectivity in later cortical stages partially inherits characteristics from earlier cortical stages and is further refined by intracortical connections. |
| format | Article |
| id | doaj-art-c87d7c8863dc484a8d4f89992910ec9c |
| institution | Kabale University |
| issn | 1544-9173 1545-7885 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS Biology |
| spelling | doaj-art-c87d7c8863dc484a8d4f89992910ec9c2025-01-17T05:30:43ZengPublic Library of Science (PLoS)PLoS Biology1544-91731545-78852025-01-01231e300294710.1371/journal.pbio.3002947Cortical direction selectivity increases from the input to the output layers of visual cortex.Weifeng DaiTian WangYang LiYi YangYange ZhangYujie WuTingting ZhouHongbo YuLiang LiYizheng WangGang WangDajun XingSensitivity to motion direction is a feature of visual neurons that is essential for motion perception. Recent studies have suggested that direction selectivity is re-established at multiple stages throughout the visual hierarchy, which contradicts the traditional assumption that direction selectivity in later stages largely derives from that in earlier stages. By recording laminar responses in areas 17 and 18 of anesthetized cats of both sexes, we aimed to understand how direction selectivity is processed and relayed across 2 successive stages: the input layers and the output layers within the early visual cortices. We found a strong relationship between the strength of direction selectivity in the output layers and the input layers, as well as the preservation of preferred directions across the input and output layers. Moreover, direction selectivity was enhanced in the output layers compared to the input layers, with the response strength maintained in the preferred direction but reduced in other directions and under blank stimuli. We identified a direction-tuned gain mechanism for interlaminar signal transmission, which likely originated from both feedforward connections across the input and output layers and recurrent connections within the output layers. This direction-tuned gain, coupled with nonlinearity, contributed to the enhanced direction selectivity in the output layers. Our findings suggest that direction selectivity in later cortical stages partially inherits characteristics from earlier cortical stages and is further refined by intracortical connections.https://doi.org/10.1371/journal.pbio.3002947 |
| spellingShingle | Weifeng Dai Tian Wang Yang Li Yi Yang Yange Zhang Yujie Wu Tingting Zhou Hongbo Yu Liang Li Yizheng Wang Gang Wang Dajun Xing Cortical direction selectivity increases from the input to the output layers of visual cortex. PLoS Biology |
| title | Cortical direction selectivity increases from the input to the output layers of visual cortex. |
| title_full | Cortical direction selectivity increases from the input to the output layers of visual cortex. |
| title_fullStr | Cortical direction selectivity increases from the input to the output layers of visual cortex. |
| title_full_unstemmed | Cortical direction selectivity increases from the input to the output layers of visual cortex. |
| title_short | Cortical direction selectivity increases from the input to the output layers of visual cortex. |
| title_sort | cortical direction selectivity increases from the input to the output layers of visual cortex |
| url | https://doi.org/10.1371/journal.pbio.3002947 |
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