Ion channels research in hPSC-RPE cells: bridging benchwork to clinical applications

Ion channels research in hPSC-RPE cells: bridging benchwork to clinical applications

Abstract Ion channels in retinal pigment epithelial (RPE) cells are crucial for retinal health and vision functions. Defects in such channels are intricately associated with the development of various retinopathies that cause blindness. Human pluripotent stem cells (hPSC)-derived RPE cells, includin...

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Bibliographic Details
Main Authors: Ping Xu, Weisheng Zou, Wenjing Yin, Guifu Chen, Guanjie Gao, Xiufeng Zhong
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Journal of Translational Medicine
Subjects:
Ion channel
hPSC-RPE
Retina
Channelopathy
Gene therapy
Online Access:https://doi.org/10.1186/s12967-024-05769-5
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