DET induces apoptosis and suppresses tumor invasion in glioma cells via PI3K/AKT pathway

DET induces apoptosis and suppresses tumor invasion in glioma cells via PI3K/AKT pathway

IntroductionGliomas, particularly glioblastomas (GBM), are highly aggressive with a poor prognosis and low survival rate. Currently, deoxyelephantopin (DET) has shown promising anti-inflammatory and anti-tumor effects. Using clinical prognostic analysis, molecular docking, and network pharmacology,...

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Bibliographic Details
Main Authors:	Rui Zhao, Mengran Wang, Zeyu Wu, Panpan Zhao, Huiling Dong, Yue Su, Chenghui Zhao, Min Qi, Shizhang Ling, Xiaochun Jiang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-01-01
Series:	Frontiers in Oncology
Subjects:	glioma cell proliferation cell apoptosis Pl3K cell invasion
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2024.1528454/full
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