Integrating Physical and Biochemical Cues for Muscle Engineering: Scaffolds and Graft Durability

Integrating Physical and Biochemical Cues for Muscle Engineering: Scaffolds and Graft Durability

Muscle stem cells (MuSCs) are essential for skeletal muscle regeneration, influenced by a complex interplay of mechanical, biochemical, and molecular cues. Properties of the extracellular matrix (ECM) such as stiffness and alignment guide stem cell fate through mechanosensitive pathways, where force...

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Bibliographic Details
Main Authors: Farbod Yousefi, Lauren Ann Foster, Omar A. Selim, Chunfeng Zhao
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Bioengineering
Subjects:
skeletal muscle regeneration
extracellular matrix
mechanotransduction
external cues
cellular senescence
fibrosis
Online Access:https://www.mdpi.com/2306-5354/11/12/1245
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