$Enhanced proteomic profiling of human plasma‐derived extracellular vesicles through charge‐based fractionation to advance biomarker discovery potential$

Enhanced proteomic profiling of human plasma‐derived extracellular vesicles through charge‐based fractionation to advance biomarker discovery potential

Abstract The study introduces a charge‐based fractionation method for fractionating plasma‐derived extracellular vesicles (EVs) into sub‐populations aimed at the improved purification from free plasma proteins to enhance the diagnostic potential of EV sub‐populations for specific pathophysiological...

Full description

Saved in:

Bibliographic Details
Main Authors:	Xianyi Su, Getúlio Pereira de Oliveira Júnior, Anne‐Lise Marie, Michal Gregus, Amanda Figueroa‐Navedo, Ionita C. Ghiran, Alexander R. Ivanov
Format:	Article
Language:	English
Published:	Wiley 2024-12-01
Series:	Journal of Extracellular Vesicles
Subjects:	EV sub‐populations extracellular vesicles ion exchange chromatography prostate cancer diagnostics proteomics
Online Access:	https://doi.org/10.1002/jev2.70024
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Challenges of MS‐based small extracellular vesicles proteomics
by: Daniel Fochtman, et al.
Published: (2024-12-01)

Venoms and Extracellular Vesicles: A New Frontier in Venom Biology
by: Auwal A. Bala, et al.
Published: (2025-01-01)

Extracellular Vesicles and Tunnelling Nanotubes as Mediators of Prostate Cancer Intercellular Communication
by: Jessica K. Heatlie, et al.
Published: (2024-12-01)

Advancing research on parasitic infections: Standardized extracellular vesicle guideline
by: Carmen Fernandez‐Becerra, et al.
Published: (2024-12-01)

A novel strategy for biomarker discovery: Neutral loss-dependent acquisition of circulating extracellular vesicles for the detection of phosphopeptides
by: Dong Wei, et al.
Published: (2025-08-01)

Analysis of small extracellular vesicles from dried blood spots
by: Rikke Bæk, et al.
Published: (2025-01-01)

Mechanistic insight into human milk extracellular vesicle‐intestinal barrier interactions
by: Xiang Luo, et al.
Published: (2025-01-01)

Extracellular vesicles, RNA sequencing, and bioinformatic analyses: Challenges, solutions, and recommendations
by: Rebecca T. Miceli, et al.
Published: (2024-12-01)

Congenital Zika Syndrome: Insights from Integrated Proteomic and Metabolomic Analysis
by: Leticia Gomes-de-Pontes, et al.
Published: (2024-12-01)

hUC-MSC extracellular vesicles protect against hypoxic-ischemic brain injury by promoting NLRP3 ubiquitination
by: Shanshan Xiao, et al.
Published: (2024-12-01)

Bacterial extracellular vesicles in the initiation, progression and treatment of atherosclerosis
by: Yuling Lin, et al.
Published: (2025-12-01)

Identification of key miRNAs and target genes in extracellular vesicles derived from low-intensity pulsed ultrasound-treated stem cells
by: Xin Yin, et al.
Published: (2025-01-01)

Oncolytic alphavirus-induced extracellular vesicles counteract the immunosuppressive effect of melanoma-derived extracellular vesicles
by: Darshak K. Bhatt, et al.
Published: (2025-01-01)

Probing aspects of extracellular vesicle associated AAV allows increased vector yield and insight into its transduction and immune-evasive properties
by: Ming Cheng, et al.
Published: (2025-03-01)

Stabilizing milk-derived extracellular vesicles (mEVs) through lyophilization: a novel trehalose and tryptophan formulation for maintaining structure and Bioactivity during long-term storage
by: Alan B. Dogan, et al.
Published: (2025-01-01)

Mesenchymal stem cells and their extracellular vesicle therapy for neurological disorders: traumatic brain injury and beyond
by: Aref Yarahmadi, et al.
Published: (2025-02-01)

Gut microbiome-derived bacterial extracellular vesicles in patients with solid tumours
by: Surbhi Mishra, et al.
Published: (2025-02-01)

Secretome – the role of extracellular vesicles in the pathogenesis and therapy of neurodegenerative diseases
by: Anna Sulek
Published: (2024-11-01)

EV‐Elute: A universal platform for the enrichment of functional surface marker‐defined extracellular vesicle subpopulations
by: Willemijn S. deVoogt, et al.
Published: (2024-12-01)

Extracellular Vesicles in Periodontitis: Pathogenic Mechanisms and Therapeutic Potential
by: Zhang L, et al.
Published: (2025-01-01)

Extracellular vesicles in thalassemia: Mechanisms, implications, and therapeutic potential
by: Shahzad Ali Jiskani
Published: (2025-06-01)

Pathogenic and therapeutic roles of extracellular vesicles in sepsis
by: Benshuai You, et al.
Published: (2025-02-01)

Impacts of Hyaluronan on Extracellular Vesicle Production and Signaling
by: Melanie A. Simpson
Published: (2025-01-01)

Opportunities and challenges of bacterial extracellular vesicles in regenerative medicine
by: Jiming Guo, et al.
Published: (2025-01-01)

Immune regulation is more effective in the U937 inflammation model with mesenchymal stem cell extracellular vesicles stimulated by pro-inflammatory cytokines
by: Canan Öztürk, et al.
Published: (2024-11-01)

Dopamine‐conjugated extracellular vesicles induce autophagy in Parkinson's disease
by: Jae Hoon Sul, et al.
Published: (2024-12-01)

Exploring RNA cargo in extracellular vesicles for pleural mesothelioma detection
by: Agnieszka Kraft, et al.
Published: (2025-02-01)

Unlocking the secrets of the immunopeptidome: MHC molecules, ncRNA peptides, and vesicles in immune response
by: Arpita Balakrishnan, et al.
Published: (2025-01-01)

Incorporation of recombinant proteins into extracellular vesicles by Lactococcus cremoris
by: Tina Vida Plavec, et al.
Published: (2025-01-01)

Circulating, Extracellular Vesicle-Associated Tissue Factor in Cancer Patients with and without Venous Thromboembolism
by: Valentina Lami, et al.
Published: (2025-01-01)

Diagnostic Value of Glycosylated Extracellular Vesicle microRNAs in Gastric Cancer
by: Wang S, et al.
Published: (2025-01-01)

Sigma1 inhibitor suppression of adaptive immune resistance mechanisms mediated by cancer cell derived extracellular vesicles
by: Paola A. Castagnino, et al.
Published: (2025-12-01)

Unveiling the wonders of bacteria-derived extracellular vesicles: From fundamental functions to beneficial applications
by: Mariam Rima, et al.
Published: (2025-02-01)

Extracellular vesicles (EVs) in seminal plasma of buffalo bulls possess spermatozoa specific fertility associated proteins and enzymes
by: Rakesh Kumar, et al.
Published: (2023-11-01)

Exercise-induced extracellular vesicles in reprogramming energy metabolism in cancer
by: Marju Puurand, et al.
Published: (2025-01-01)

Therapeutic potential of mesenchymal stem cells and stem cell-derived extracellular vesicles in tuberculosis of various localizations: A review
by: Veronika V. Shumko, et al.
Published: (2024-10-01)

Interplay between extracellular vesicles and allergic diseases: Current insights and future perspectives
by: Jia Wu, et al.
Published: (2025-01-01)

Magnetoelectric Extracellular Vesicle Latency-Targeting (MELT) Nanotherapeutic for the Block-Lock-and-Kill HIV Eradication Strategy
by: Mickensone Andre, et al.
Published: (2025-01-01)

The impact of Aureobasidium melanogenum cells and extracellular vesicles on human cell lines
by: Anja Černoša, et al.
Published: (2025-01-01)

Muscle-derived extracellular vesicles mediate crosstalk between skeletal muscle and other organs
by: Jiajie Jia, et al.
Published: (2025-01-01)